Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …

Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …

BACKGROUND The escalating crisis of multidrug resistance is raising fears of untreatable
infections caused by bacterial “superbugs.” However, many patients already suffer from …

The incidence of fungal infections has increased significantly, so contributing to morbidity
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …

Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Bacterial persister cells are phenotypic variants that exhibit a transient non-growing state
and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus …

Background The airways of patients with cystic fibrosis (CF) are highly complex, subject to
various environmental conditions as well as a distinct microbiota. Pseudomonas aeruginosa …

Acinetobacter baumannii (A. baumannii) is a leading cause of nosocomial infections as this
pathogen has certain attributes that facilitate the subversion of natural defenses of the …

The great therapeutic achievements of antibiotics have been dramatically undercut by the
evolution of bacterial strategies that overcome antibiotic stress,. These strategies fall into two …