In the past decade, relative proteomic quantification using isobaric labeling technology has
developed into a key tool for comparing the expression of proteins in biological samples …

Ferroptosis is a regulated form of necrotic cell death caused by iron-dependent
accumulation of oxidized phospholipids in cellular membranes, culminating in plasma …

Abstract Filter Aided Sample Preparation (FASP) is a widely used protein processing
technique in “bottom-up” proteomics. Its popularity reflects the key features of the method: its …

Universal proteomics sample preparation is challenging because of the high heterogeneity
of biological samples. Here we describe a novel mechanism that exploits the inherent …

Biofilm formation is generally recognized as a bacterial defense mechanism against
environmental threats, including antibiotics, bacteriophages, and leukocytes of the human …

Red blood cells (RBCs) are the most abundant cell type in the human body. RBCs and, in
particular, their plasma membrane composition have been extensively studied for many …

The main challenge of bottom-up proteomic sample preparation is to extract proteomes in a
manner that enables efficient protein digestion for subsequent mass spectrometric analysis …

The peripheral nervous system harbors a remarkable potential to regenerate after acute
nerve trauma. Full functional recovery, however, is rare and critically depends on peripheral …

Filter aided sample preparation (FASP) and related methods gain increasing popularity for
proteomic sample preparation. Nevertheless, the originally published FASP method has …

Lipid droplets (LDs) are dynamic lipid storage organelles. They are tightly linked to
metabolism and can exert protective functions, making them important players in health and …