Criteria for the translation of radiomics into clinically useful tests
EP Huang, JPB O'Connor, LM McShane… - Nature reviews Clinical …, 2023 - nature.com
Computer-extracted tumour characteristics have been incorporated into medical imaging
computer-aided diagnosis (CAD) algorithms for decades. With the advent of radiomics, an …
computer-aided diagnosis (CAD) algorithms for decades. With the advent of radiomics, an …
Imaging biomarker roadmap for cancer studies
JPB O'connor, EO Aboagye, JE Adams… - Nature reviews Clinical …, 2017 - nature.com
Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs
used daily in oncology include clinical TNM stage, objective response and left ventricular …
used daily in oncology include clinical TNM stage, objective response and left ventricular …
Imaging intratumor heterogeneity: role in therapy response, resistance, and clinical outcome
Tumors exhibit genomic and phenotypic heterogeneity, which has prognostic significance
and may influence response to therapy. Imaging can quantify the spatial variation in …
and may influence response to therapy. Imaging can quantify the spatial variation in …
Models and methods for analyzing DCE‐MRI: A review
Purpose: To present a review of most commonly used techniques to analyze dynamic
contrast‐enhanced magnetic resonance imaging (DCE‐MRI), discusses their strengths and …
contrast‐enhanced magnetic resonance imaging (DCE‐MRI), discusses their strengths and …
Clinical development of new drug–radiotherapy combinations
RA Sharma, R Plummer, JK Stock… - Nature reviews Clinical …, 2016 - nature.com
In countries with the best cancer outcomes, approximately 60% of patients receive
radiotherapy as part of their treatment, which is one of the most cost-effective cancer …
radiotherapy as part of their treatment, which is one of the most cost-effective cancer …
[HTML][HTML] Assessment of blood–brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review
AK Heye, RD Culling, MCV Hernández… - NeuroImage: Clinical, 2014 - Elsevier
There is increasing recognition of the importance of blood–brain barrier (BBB) disruption in
aging, dementia, stroke and multiple sclerosis in addition to more commonly-studied …
aging, dementia, stroke and multiple sclerosis in addition to more commonly-studied …
The transformation of radiation oncology using real-time magnetic resonance guidance: A review
WA Hall, ES Paulson, UA van der Heide… - European Journal of …, 2019 - Elsevier
Radiation therapy (RT) is an essential component of effective cancer care and is used
across nearly all cancer types. The delivery of RT is becoming more precise through rapid …
across nearly all cancer types. The delivery of RT is becoming more precise through rapid …
Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models
Y Funahashi, K Okamoto, Y Adachi, T Semba… - Cancer …, 2014 - Wiley Online Library
Eribulin mesylate is a synthetic macrocyclic ketone analog of the marine sponge natural
product halichondrin B and an inhibitor of microtubule dynamics. Some tubulin‐binding …
product halichondrin B and an inhibitor of microtubule dynamics. Some tubulin‐binding …
Ferroptosis MRI for early detection of anticancer drug–induced acute cardiac/kidney injuries
F Zeng, S Nijiati, Y Liu, Q Yang, X Liu, Q Zhang… - Science …, 2023 - science.org
Ferroptosis has been realized in anticancer drug–induced acute cardiac/kidney injuries
(ACI/AKI); however, molecular imaging approach to detect ferroptosis in ACI/AKI is a …
(ACI/AKI); however, molecular imaging approach to detect ferroptosis in ACI/AKI is a …
Markers of response for the antiangiogenic agent bevacizumab
Bevacizumab is the first antiangiogenic therapy proven to slow metastatic disease
progression in patients with cancer. Although it has changed clinical practice, some patients …
progression in patients with cancer. Although it has changed clinical practice, some patients …