Chromogenic and fluorogenic probes may be described as the reagents that can interact
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …

Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Herein, we describe an energy balance strategy between fluorescence and photoacoustic
effects by sulfur substitution to transform existing hemicyanine dyes (Cy) into optimized …

Nitroreductase (NTR) can be overexpressed in hypoxic tumors, thus the selective and
efficient detection of NTR is of great importance. To date, although a few optical methods …

The review deals with commercially available organic dyes possessing large Stokes shifts
and their applications as fluorescent labels in optical microscopy based on stimulated …

Apart from numerous applications, for example in azo dye precursors, explosives, and
industrial processes, the nitro group (− NO2) appears on countless molecules in …

As one of the most representative hypoxic enzymes, nitroreductases (NTRs) play
momentous roles in malignant tumor progression, metastasis, invasion and angiogenesis …

A highly selective and sensitive fluorescence probe, 7-[(5-nitrofuran-2-yl) methoxy]-3 H-
phenoxazin-3-one (1), is developed for imaging the hypoxic status of tumor cells via the …

A new near-infrared fluorescence off–on probe is developed and applied to fluorescence
imaging of nitroreductase in zebrafish in vivo. The probe is readily prepared by connecting 4 …

Hypoxia plays an important role in tumor progression, and the development of efficient
methods for monitoring hypoxic degree in living systems is of great biomedical importance …