The molecular mechanisms of copper metabolism and its roles in human diseases
J Chen, Y Jiang, H Shi, Y Peng, X Fan, C Li - Pflügers Archiv-European …, 2020 - Springer
Copper is an essential element in cells; it can act as either a recipient or a donor of
electrons, participating in various reactions. However, an excess of copper ions in cells is …
electrons, participating in various reactions. However, an excess of copper ions in cells is …
The molecular and cellular basis of copper dysregulation and its relationship with human pathologies
MT Maung, A Carlson, M Olea‐Flores… - The FASEB …, 2021 - Wiley Online Library
Copper (Cu) is an essential micronutrient required for the activity of redox‐active enzymes
involved in critical metabolic reactions, signaling pathways, and biological functions …
involved in critical metabolic reactions, signaling pathways, and biological functions …
[HTML][HTML] Role of copper in human neurological disorders
V Desai, SG Kaler - The American journal of clinical nutrition, 2008 - Elsevier
Copper is a trace element present in all tissues and is required for cellular respiration,
peptide amidation, neurotransmitter biosynthesis, pigment formation, and connective tissue …
peptide amidation, neurotransmitter biosynthesis, pigment formation, and connective tissue …
Prion diseases
MD Geschwind - CONTINUUM: Lifelong Learning in Neurology, 2015 - journals.lww.com
Abstract Purpose of Review: This article presents an update on the clinical aspects of human
prion disease, including the wide spectrum of their presentations. Recent Findings: Prion …
prion disease, including the wide spectrum of their presentations. Recent Findings: Prion …
[LIBRO][B] Principles of molecular virology
A Cann - 2001 - books.google.com
Principles of Molecular Virology, Third Edition provides an essential introduction to modern
virology in a clear and concise manner. It is a highly enjoyable and readable text with …
virology in a clear and concise manner. It is a highly enjoyable and readable text with …
[HTML][HTML] Prion disease in dromedary camels, Algeria
B Babelhadj, MA Di Bari, L Pirisinu… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
Prions cause fatal and transmissible neurodegenerative diseases, including Creutzfeldt-
Jakob disease in humans, scrapie in small ruminants, and bovine spongiform …
Jakob disease in humans, scrapie in small ruminants, and bovine spongiform …
Oral transmissibility of prion disease is enhanced by binding to soil particles
CJ Johnson, JA Pedersen, RJ Chappell… - PLoS …, 2007 - journals.plos.org
Soil may serve as an environmental reservoir for prion infectivity and contribute to the
horizontal transmission of prion diseases (transmissible spongiform encephalopathies …
horizontal transmission of prion diseases (transmissible spongiform encephalopathies …
Autophagy regulates exosomal release of prions in neuronal cells
BA Abdulrahman, DH Abdelaziz, HM Schatzl - Journal of Biological …, 2018 - ASBMB
Prions are protein-based infectious agents that autocatalytically convert the cellular prion
protein PrP C to its pathological isoform PrP Sc. Subsequent aggregation and accumulation …
protein PrP C to its pathological isoform PrP Sc. Subsequent aggregation and accumulation …
Cellular copper homeostasis: current concepts on its interplay with glutathione homeostasis and its implication in physiology and human diseases
A Bhattacharjee, K Chakraborty, A Shukla - Metallomics, 2017 - academic.oup.com
Copper is a trace element essential for almost all living organisms. But the level of
intracellular copper needs to be tightly regulated. Dysregulation of cellular copper …
intracellular copper needs to be tightly regulated. Dysregulation of cellular copper …
Intercommunication between metal ions and amyloidogenic peptides or proteins in protein misfolding disorders
The aggregation and accumulation of amyloidogenic peptides and proteins are observed as
pathological features in the brains of patients suffering from neurodegenerative disorders …
pathological features in the brains of patients suffering from neurodegenerative disorders …