Dynamics of the actin cytoskeleton mediates receptor cross talk: An emerging concept in tuning receptor signaling
Recent evidence implicates the actin cytoskeleton in the control of receptor signaling. This
may be of particular importance in the context of immune receptors, such as the B cell …
may be of particular importance in the context of immune receptors, such as the B cell …
MHC class I–restricted CTL responses to exogenous antigens
M Jondal, R Schirmbeck, J Reimann - Immunity, 1996 - cell.com
Introduction thelial cells), which, however, could not respond to the Different processing
pathways operate for major histonucleoprotein-transfected tumor cells, demonstrating a …
pathways operate for major histonucleoprotein-transfected tumor cells, demonstrating a …
Cell‐surface expression and immune receptor recognition of HLA–B27 homodimers
Objective HLA–B27 is capable of forming in vitro a heavy‐chain homodimer structure
lacking β2‐microglobulin. We undertook this study to ascertain if patients with …
lacking β2‐microglobulin. We undertook this study to ascertain if patients with …
Receptor crosslinking: a general method to trigger internalization and lysosomal targeting of therapeutic receptor: ligand complexes
A major unmet clinical need is a universal method for subcellular targeting of bioactive
molecules to lysosomes. Delivery to this organelle enables either degradation of oncogenic …
molecules to lysosomes. Delivery to this organelle enables either degradation of oncogenic …
Lymphoblastoid cells express HLA‐B27 homodimers both intracellularly and at the cell surface following endosomal recycling
LA Bird, CA Peh, S Kollnberger, T Elliott… - European journal of …, 2003 - Wiley Online Library
The MHC class I allele HLA‐B27 is very strongly associated with development of
autoimmune spondyloarthritis, although the disease mechanism remains unknown. Class I …
autoimmune spondyloarthritis, although the disease mechanism remains unknown. Class I …
Anomalous diffusion of major histocompatibility complex class I molecules on HeLa cells determined by single particle tracking
PR Smith, IEG Morrison, KM Wilson, N Fernandez… - Biophysical journal, 1999 - cell.com
Single-particle tracking (SPT) was used to determine the mobility characteristics of MHC
(major histocompatibility complex) class I molecules at the surface of HeLa cells at 22° C …
(major histocompatibility complex) class I molecules at the surface of HeLa cells at 22° C …
HLA class I allelic sequence and conformation regulate leukocyte Ig-like receptor binding
Abstract Leukocyte Ig-like receptors (LILRs) are a family of innate immune receptors
predominantly expressed by myeloid cells that can alter the Ag presentation properties of …
predominantly expressed by myeloid cells that can alter the Ag presentation properties of …
Cutting edge: leukocyte receptor complex-encoded immunomodulatory receptors show differing specificity for alternative HLA-B27 structures
We studied recognition of the disease-associated HLA-B27 allele by immunomodulatory
receptors encoded within the leukocyte receptor complex. HLA class I are ligands for …
receptors encoded within the leukocyte receptor complex. HLA class I are ligands for …
Autophagy‐dependent regulation of MHC‐I molecule presentation
U Gestal‐Mato, L Herhaus - Journal of Cellular Biochemistry, 2024 - Wiley Online Library
The major histocompatibility complex (MHC) class I molecules present peptide antigens to
MHC class I‐restricted CD8+ T lymphocytes to elicit an effective immune response. The …
MHC class I‐restricted CD8+ T lymphocytes to elicit an effective immune response. The …
Activation-dependent clustering of the erbB2 receptor tyrosine kinase detected by scanning near-field optical microscopy
ABSTRACT ErbB2 (HER2, Neu), a member of the epidermal growth factor (EGF) receptor
tyrosine kinase family, is often overexpressed in breast cancer and other malignancies …
tyrosine kinase family, is often overexpressed in breast cancer and other malignancies …