The immunological life cycle of tuberculosis
JD Ernst - Nature Reviews Immunology, 2012 - nature.com
Immune responses to Mycobacterium tuberculosis are only partially effective; they drive the
bacteria into a latent state, but rarely eliminate them. Unfortunately, the latent state of M …
bacteria into a latent state, but rarely eliminate them. Unfortunately, the latent state of M …
CCR5 and CCR5Δ32 in bacterial and parasitic infections: Thinking chemokine receptors outside the HIV box
The CCR5 molecule was reported in 1996 as the main HIV‐1 co‐receptor. In that same year,
the CCR5Δ32 genetic variant was described as a strong protective factor against HIV‐1 …
the CCR5Δ32 genetic variant was described as a strong protective factor against HIV‐1 …
A functional single-nucleotide polymorphism in the promoter of the gene encoding interleukin 6 is associated with susceptibility to tuberculosis
G Zhang, B Zhou, W Wang, M Zhang… - The Journal of …, 2012 - academic.oup.com
Background Genetic variation influences susceptibility or resistance to tuberculosis.
Interleukin 6 (IL-6) contributes to protection against tuberculosis in mice. However, its role in …
Interleukin 6 (IL-6) contributes to protection against tuberculosis in mice. However, its role in …
Correlating multiallelic copy number polymorphisms with disease susceptibility
S Cantsilieris, SJ White - Human mutation, 2013 - Wiley Online Library
The human genome contains a significant amount of sequence variation, from single
nucleotide polymorphisms to large stretches of DNA that may be present in a range of …
nucleotide polymorphisms to large stretches of DNA that may be present in a range of …
Cellular and humoral immune responses during tuberculosis infection: useful knowledge in the era of biological agents
A Matucci, E Maggi, A Vultaggio - The Journal of Rheumatology …, 2014 - jrheum.org
In this review, recent insights into innate and adaptive cellular and humoral immune
response to Mycobacterium tuberculosis (Mtb) are discussed and the role of specific …
response to Mycobacterium tuberculosis (Mtb) are discussed and the role of specific …
The role of host genetics (and genomics) in tuberculosis
V Naranbhai - Microbiology Spectrum, 2016 - Am Soc Microbiol
Familial risk of tuberculosis (TB) has been recognized for centuries. Largely through studies
of mono-and dizygotic twin concordance rates, studies of families with Mendelian …
of mono-and dizygotic twin concordance rates, studies of families with Mendelian …
Immunogenetics of HIV and HIV associated tuberculosis
S Raghavan, K Alagarasu, P Selvaraj - Tuberculosis, 2012 - Elsevier
Tuberculosis (TB) is the frequent major opportunistic infection in HIV-infected patients, and is
the leading cause of mortality among HIV-infected patients. Genetic susceptibility to TB in …
the leading cause of mortality among HIV-infected patients. Genetic susceptibility to TB in …
Host Genetic Impact on Infectious Diseases among Different Ethnic Groups
L Naidoo, T Arumugam, V Ramsuran - Advanced Genetics, 2023 - Wiley Online Library
Infectious diseases such as malaria, tuberculosis (TB), human immunodeficiency virus (HIV),
and the coronavirus disease of 2019 (COVID‐19) are problematic globally, with high …
and the coronavirus disease of 2019 (COVID‐19) are problematic globally, with high …
Genetic variants in the chemokines and chemokine receptors in Chagas disease
Clinical symptoms of Chagas' disease occur in 30% of the individuals infected with
Trypanosoma cruzi and are characterised by heart inflammation and dysfunction …
Trypanosoma cruzi and are characterised by heart inflammation and dysfunction …
CCL3L1 copy number, CCR5genotype and susceptibility to tuberculosis
Background Tuberculosis is a major infectious disease and functional studies have provided
evidence that both the chemokine MIP-1α and its receptor CCR5 play a role in susceptibility …
evidence that both the chemokine MIP-1α and its receptor CCR5 play a role in susceptibility …