Lung cancer (LC) is a heterogeneous disease with high malignant degree, rapid growth,
and early metastasis. The clinical outcomes of LC patients are generally poor due to the …

Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …

Psoriasis is an intractable immune-mediated disorder that disrupts the skin barrier. While
studies have dissected the mechanism by which immune cells directly regulate epidermal …

The tumor microenvironment (TME) is a complex interconnected network of immune cells,
fibroblasts, blood vessels, and extracellular matrix surrounding the tumor. Because of its …

Prostate cancer (PCa) progression leads to bone modulation in approximately 70% of
affected men. A nutraceutical, namely, α-lipoic acid (α-LA), is known for its potent anti-cancer …

For several decades, most lung cancer investigations have focused on the search for
mutations in candidate genes; however, in the last decade, due to the fact that most of the …

Background Cells have been increasingly known to release extracellular vesicles (EVs) to
the extracellular environment under physiological and pathological conditions. A plethora of …

Lung cancer, as the most commonly diagnosed malignancy, still accounts for the leading
cause of cancer-related deaths worldwide. The high rate of mortality and tumor recurrence …

The present study aimed to investigate the role and mechanism of action of ribonucleotide
reductase M2 (RRM2) in lung adenocarcinoma and its potential as a therapeutic target. Data …

Abstract N6-methyladenosine (m6A) methylation, a prevalent eukaryotic post-transcriptional
modification, is involved in multiple biological functions, including mediating variable …