Advances of zebrafish in neurodegenerative disease: from models to drug discovery

X Wang, JB Zhang, KJ He, F Wang… - Frontiers in Pharmacology, 2021 - frontiersin.org
Neurodegenerative disease (NDD), including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …

Cotinine: pharmacologically active metabolite of nicotine and neural mechanisms for its actions

X Tan, K Vrana, ZM Ding - Frontiers in Behavioral Neuroscience, 2021 - frontiersin.org
Tobacco use disorder continues to be a leading public health issue and cause of premature
death in the United States. Nicotine is considered as the major tobacco alkaloid causing …

[HTML][HTML] Environmental occurrence and ecological risks of psychoactive substances

H **, D Yang, P Wu, M Zhao - Environment international, 2022 - Elsevier
Psychoactive substances are ubiquitous in the environment at low concentrations, and
tobacco, cannabis, etc. are all widely-existing examples. Given their potent biological …

The brilliance of the zebrafish model: perception on behavior and Alzheimer's disease

A Shenoy, M Banerjee, A Upadhya… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) has become increasingly prevalent in the elderly population
across the world. It's pathophysiological markers such as overproduction along with the …

Zebrafish: A pharmacological model for learning and memory research

JK Tan, FH Nazar, S Makpol, SL Teoh - Molecules, 2022 - mdpi.com
Learning and memory are essential to organism survival and are conserved across various
species, especially vertebrates. Cognitive studies involving learning and memory require …

Direct Evidence for Using Coriandrum sativum var. microcarpum Essential Oil to Ameliorate Scopolamine-Induced Memory Impairment and Brain Oxidative Stress in …

I Brinza, RS Boiangiu, O Cioanca, M Hancianu… - Antioxidants, 2023 - mdpi.com
Essential oil from Coriandrum sativum has been demonstrated to provide various
pharmacological properties, such as antioxidant, antimicrobial, antibacterial, antifungal …

An update in recent research on nicotine contamination and nicotine-degrading microorganisms

M Deng, P Basak, Y Zhang, J Song, H Suo - Toxicon, 2024 - Elsevier
Nicotine is a toxic and addictive alkaloid found in tobacco and tobacco products that is
harmful to human health and is an environmental pollutant. Nicotine-degrading …

Nicotinic acetylcholine receptors and learning and memory deficits in Neuroinflammatory diseases

V Echeverria, C Mendoza, A Iarkov - Frontiers in Neuroscience, 2023 - frontiersin.org
Animal survival depends on cognitive abilities such as learning and memory to adapt to
environmental changes. Memory functions require an enhanced activity and connectivity of …

Fructus gardeniae ameliorates anxiety-like behaviors induced by sleep deprivation via regulating hippocampal metabolomics and gut microbiota

D Liu, Q Wang, Y Li, Z Yuan, Z Liu, J Guo… - Frontiers in Cellular …, 2023 - frontiersin.org
Fructus gardeniae (FG) is a traditional Chinese medicine and health food for thousands of
years of application throughout Chinese history and is still widely used in clinical Chinese …

Zebrafish models for studying cognitive enhancers

TO Kolesnikova, KA Demin, FV Costa… - Neuroscience & …, 2024 - Elsevier
Cognitive decline is commonly seen both in normal aging and in neurodegenerative and
neuropsychiatric diseases. Various experimental animal models represent a valuable tool to …