Updates to the modern diagnosis of GERD: Lyon consensus 2.0
The Lyon Consensus provides conclusive criteria for and against the diagnosis of gastro-
oesophageal reflux disease (GERD), and adjunctive metrics that consolidate or refute GERD …
oesophageal reflux disease (GERD), and adjunctive metrics that consolidate or refute GERD …
ACG clinical guideline for the diagnosis and management of gastroesophageal reflux disease
Gastroesophageal reflux disease (GERD) continues to be among the most common
diseases seen by gastroenterologists, surgeons, and primary care physicians. Our …
diseases seen by gastroenterologists, surgeons, and primary care physicians. Our …
Safety of proton pump inhibitors based on a large, multi-year, randomized trial of patients receiving rivaroxaban or aspirin
Background & Aims Proton pump inhibitors (PPIs) are effective at treating acid-related
disorders. These drugs are well tolerated in the short term, but long-term treatment was …
disorders. These drugs are well tolerated in the short term, but long-term treatment was …
Deprescribing proton pump inhibitors: evidence-based clinical practice guideline
Objective To develop an evidence-based guideline to help clinicians make decisions about
when and how to safely taper or stop proton pump inhibitors (PPIs); to focus on the highest …
when and how to safely taper or stop proton pump inhibitors (PPIs); to focus on the highest …
Management of gastroesophageal reflux disease
CP Gyawali, R Fass - Gastroenterology, 2018 - Elsevier
Management of gastroesophageal reflux disease (GERD) commonly starts with an empiric
trial of proton pump inhibitor (PPI) therapy and complementary lifestyle measures, for …
trial of proton pump inhibitor (PPI) therapy and complementary lifestyle measures, for …
Health outcomes of deprescribing interventions among older residents in nursing homes: a systematic review and meta-analysis
Objectives Deprescribing is effective in addressing concerns relating to polypharmacy in
residents of nursing homes. However, the clinical outcomes of deprescribing interventions …
residents of nursing homes. However, the clinical outcomes of deprescribing interventions …
The global, regional, and national burden of gastro-oesophageal reflux disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global …
Background Gastro-oesophageal reflux disease is a common chronic ailment that causes
uncomfortable symptoms and increases the risk of oesophageal adenocarcinoma. We …
uncomfortable symptoms and increases the risk of oesophageal adenocarcinoma. We …
Individualized prevention of proton pump inhibitor related adverse events by risk stratification
B **a, Q He, FG Smith, VG Gkoutos… - Nature …, 2024 - nature.com
Proton pump inhibitors (PPIs) are commonly used for gastric acid-related disorders, but their
safety profile and risk stratification for high-burden diseases need further investigation …
safety profile and risk stratification for high-burden diseases need further investigation …
Impact of deprescribing interventions in older hospitalised patients on prescribing and clinical outcomes: a systematic review of randomised trials
Background Polypharmacy and potentially inappropriate medications (PIMs) are prevalent
in older adults in hospital, and are associated with negative outcomes including adverse …
in older adults in hospital, and are associated with negative outcomes including adverse …
Proton pump inhibitors and the kidney: implications of current evidence for clinical practice and when and how to deprescribe
Proton pump inhibitors (PPIs), long thought to be safe, are associated with a number of
nonkidney adverse health outcomes and several untoward kidney outcomes, including …
nonkidney adverse health outcomes and several untoward kidney outcomes, including …