Salivary glands adenoid cystic carcinoma: a molecular profile update and potential implications

FJ da Silva, J Carvalho de Azevedo Jr… - Frontiers in …, 2023 - frontiersin.org
Adenoid cystic carcinoma (ACC) is an aggressive tumor with a high propensity for distant
metastasis and perineural invasion. This tumor is more commonly found in regions of the …

Adenoid cystic carcinoma: emerging role of translocations and gene fusions

PT Wysocki, E Izumchenko, J Meir, PK Ha… - …, 2016 - pmc.ncbi.nlm.nih.gov
Adenoid cystic carcinoma (ACC), the second most common salivary gland malignancy, is
notorious for poor prognosis, which reflects the propensity of ACC to progress to clinically …

[HTML][HTML] MYB promotes the growth and metastasis of salivary adenoid cystic carcinoma

LH Xu, F Zhao, WW Yang… - International …, 2019 - spandidos-publications.com
The incidence of recurrent t (6; 9) translocation of the MYB proto‑oncogene to NFIB (the
gene that encodes nuclear factor 1 B‑type) in adenoid cystic carcinoma (ACC) tumour …

[HTML][HTML] Solid-basaloid adenoid cystic carcinoma of the breast: an aggressive subtype enriched for notch pathway and chromatin modifier mutations with MYB …

ER Shamir, GR Bean, CJ Schwartz, P Vohra, A Wang… - Modern Pathology, 2023 - Elsevier
Adenoid cystic carcinoma (AdCC) is a rare triple-negative breast cancer analogous to its
extramammary counterparts. Diagnosis of the more aggressive solid-basaloid variant of …

Immunohistochemical profile of polymorphous adenocarcinoma of minor salivary gland: a systematic review and meta-analysis

T Nonaka, H Takei - Head and Neck Pathology, 2022 - Springer
Polymorphous adenocarcinoma (PAC) is a rare variant of minor salivary gland tumors.
Because of its architectural diversity, histological diagnosis of PAC can be difficult especially …

Practical immunohistochemistry in the classification of salivary gland neoplasms

KE Higgins, NA Cipriani - Seminars in Diagnostic Pathology, 2022 - Elsevier
Diagnosis of salivary gland neoplasms can be challenging for surgical pathologists due to
low incidence of tumors as well as overlap** histologic features. On small biopsy, the most …

Diagnostic utility of p63/p40 in the histologic differentiation of salivary gland tumors: a systematic review

N Sivakumar, A Narwal, D Pandiar, A Devi… - Oral Surgery, Oral …, 2022 - Elsevier
Objective Salivary gland tumors are a heterogeneous group of neoplasms with complex
clinicopathologic behavior. These tumors often show an extremely diverse morphology and …

Clinicopathological features of 26 intraoral polymorphous adenocarcinomas from a single Brazilian institution

SN de Aquino, CVBL de Cáceres, HKF Bezerra… - Head and Neck …, 2024 - Springer
Purpose This study describes a large, well-documented case series of salivary gland
polymorphous adenocarcinomas (PAC) from a single Brazilian center. Methods …

SOX10 and GATA3 in adenoid cystic carcinoma and polymorphous adenocarcinoma

BD Adkins, A Geromes, LY Zhang, R Chernock… - Head and Neck …, 2020 - Springer
Differentiating between adenoid cystic carcinoma (AdCC) and polymorphous
adenocarcinoma (PAC) can be difficult on small biopsies and cytologic specimens. As such …

MYB expression: potential role in separating adenoid cystic carcinoma (ACC) from pleomorphic adenoma (PA)

A Moon, C Cohen, MT Siddiqui - Diagnostic cytopathology, 2016 - Wiley Online Library
Background Basaloid tumors of the salivary gland both benign and malignant comprise
ACC, cellular PA, basal cell adenoma (BCA), and basal cell adenocarcinoma. Rendering a …