Chasing bacterial chassis for metabolic engineering: a perspective review from classical to non‐traditional microorganisms

P Calero, PI Nikel - Microbial Biotechnology, 2019 - Wiley Online Library
The last few years have witnessed an unprecedented increase in the number of novel
bacterial species that hold potential to be used for metabolic engineering. Historically …

[HTML][HTML] Modular engineering for microbial production of carotenoids

C Li, CA Swofford, AJ Sinskey - Metabolic Engineering Communications, 2020 - Elsevier
There is an increasing demand for carotenoids due to their applications in the food, flavor,
pharmaceutical and feed industries, however, the extraction and synthesis of these …

Recent advances of metabolic engineering strategies in natural isoprenoid production using cell factories

M Li, F Hou, T Wu, X Jiang, F Li, H Liu, M **an… - Natural Product …, 2020 - pubs.rsc.org
Covering: up to 2019 As abundant natural products, isoprenoids have many useful industrial
applications in the manufacturing of drugs, fragrances, food additives, colorants, rubber and …

Microbial Platform for Terpenoid Production: Escherichia coli and Yeast

C Wang, M Liwei, JB Park, SH Jeong, G Wei… - Frontiers in …, 2018 - frontiersin.org
Terpenoids, also called isoprenoids, are a large and highly diverse family of natural
products with important medical and industrial properties. However, a limited production of …

[HTML][HTML] Carotenoids in drug discovery and medicine: pathways and molecular targets implicated in human diseases

DS Metibemu, IV Ogungbe - Molecules, 2022 - mdpi.com
Carotenoids are isoprenoid-derived natural products produced in plants, algae, fungi, and
photosynthetic bacteria. Most animals cannot synthesize carotenoids because the …

Effect of Genomic Integration Location on Heterologous Protein Expression and Metabolic Engineering in E. coli

JA Englaender, JA Jones, BF Cress… - ACS Synthetic …, 2017 - ACS Publications
Chromosomal integration offers a selection-free alternative to DNA plasmids for expression
of foreign proteins and metabolic pathways. Episomal plasmid DNA is convenient but has …

Reprogramming microorganisms for the biosynthesis of astaxanthin via metabolic engineering

X Wan, XR Zhou, G Moncalian, L Su, WC Chen… - Progress in lipid …, 2021 - Elsevier
There is an increasing demand for astaxanthin in food, feed, cosmetics and pharmaceutical
applications because of its superior anti-oxidative and coloring properties. However …

Metabolic Engineering of Corynebacterium glutamicum for the High-Level Production of Cadaverine That Can Be Used for the Synthesis of Biopolyamide 510

HT Kim, KA Baritugo, YH Oh, SM Hyun… - ACS Sustainable …, 2018 - ACS Publications
Fermentative production of cadaverine from renewable resources may support a sustainable
biorefinery process to produce carbon-neutral nylons such as biopolyamide 510 (PA510) …

Toward improved terpenoids biosynthesis: strategies to enhance the capabilities of cell factories

E Fordjour, EO Mensah, Y Hao, Y Yang, X Liu… - Bioresources and …, 2022 - Springer
Terpenoids form the most diversified class of natural products, which have gained
application in the pharmaceutical, food, transportation, and fine and bulk chemical …

Stable Platform for Mevalonate Bioproduction from CO2

M Garavaglia, C McGregor… - ACS Sustainable …, 2024 - ACS Publications
Stable production of value-added products using a microbial chassis is pivotal for
determining the industrial suitability of the engineered biocatalyst. Microbial cells often lose …