Biomaterial-based antimicrobial therapies for the treatment of bacterial infections

PP Kalelkar, M Riddick, AJ García - Nature Reviews Materials, 2022 - nature.com
The rise in antibiotic-resistant bacteria, including strains that are resistant to last-resort
antibiotics, and the limited ability of antibiotics to eradicate biofilms have necessitated the …

Antibiotic‐free antibacterial strategies enabled by nanomaterials: progress and perspectives

Y Wang, Y Yang, Y Shi, H Song, C Yu - Advanced Materials, 2020 - Wiley Online Library
Bacterial infection is one of the top ten leading causes of death globally and the worst killer
in low‐income countries. The overuse of antibiotics leads to ever‐increasing antibiotic …

The global preclinical antibacterial pipeline

U Theuretzbacher, K Outterson, A Engel… - Nature Reviews …, 2020 - nature.com
Antibacterial resistance is a great concern and requires global action. A critical question is
whether enough new antibacterial drugs are being discovered and developed. A review of …

[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

Z Pang, R Raudonis, BR Glick, TJ Lin, Z Cheng - Biotechnology advances, 2019 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …

Nanotechnology-based antimicrobials and delivery systems for biofilm-infection control

Y Liu, L Shi, L Su, HC van der Mei, PC Jutte… - Chemical Society …, 2019 - pubs.rsc.org
Bacterial-infections are mostly due to bacteria in an adhering, biofilm-mode of growth and
not due to planktonically growing, suspended-bacteria. Biofilm-bacteria are much more …

Multifaceted application of silica nanoparticles. A review

PG Jeelani, P Mulay, R Venkat, C Ramalingam - Silicon, 2020 - Springer
Nanoparticles have immense industrial, biotechnological, and biomedical/pharmaceutical
applications due to their pliability in structure, size, biocompatibility, high surface area, and …

Microneedle patch integrated with porous silicon confined dual nanozymes for synergistic and hyperthermia‐enhanced nanocatalytic ferroptosis treatment of …

J Zhao, W Duan, X Liu, F **, J Wu - Advanced Functional …, 2023 - Wiley Online Library
Superficial melanoma is the deadliest form of skin cancer without desirable clinically
therapeutic options. Nanozymes, artificial nanomaterials with physicochemical performance …

Silica nanoparticles—a versatile tool for the treatment of bacterial infections

V Selvarajan, S Obuobi, PLR Ee - Frontiers in Chemistry, 2020 - frontiersin.org
The rapid emergence of drug resistance continues to outpace the development of new
antibiotics in the treatment of infectious diseases. Conventional therapy is currently limited …

Non-traditional antibacterial therapeutic options and challenges

U Theuretzbacher, LJV Piddock - Cell host & microbe, 2019 - cell.com
The global challenges presented by drug-resistant bacterial infections have stimulated much
activity in finding new treatments. This review summarizes the progress and setbacks of non …

A comprehensive review of synthesis, applications and future prospects for silica nanoparticles (SNPs)

F Akhter, AA Rao, MN Abbasi, SA Wahocho, MA Mallah… - Silicon, 2022 - Springer
Silica nanoparticles (SNPs) have shown great applicability potential in a number of fields
like chemical, biomedical, biotechnology, agriculture, environmental remediation and even …