[HTML][HTML] PRRSV structure, replication and recombination: Origin of phenotype and genotype diversity

MA Kappes, KS Faaberg - Virology, 2015 - Elsevier
Porcine reproductive and respiratory disease virus (PRRSV) has the intrinsic ability to adapt
and evolve. After 25 years of study, this persistent pathogen has continued to frustrate efforts …

Arterivirus molecular biology and pathogenesis

EJ Snijder, M Kikkert, Y Fang - Journal of General …, 2013 - microbiologyresearch.org
Arteriviruses are positive-stranded RNA viruses that infect mammals. They can cause
persistent or asymptomatic infections, but also acute disease associated with a respiratory …

The PRRSV replicase: exploring the multifunctionality of an intriguing set of nonstructural proteins

Y Fang, EJ Snijder - Virus research, 2010 - Elsevier
Our knowledge about the structure and function of the nonstructural proteins (nsps) encoded
by the arterivirus replicase gene has advanced in recent years. The continued …

The 30-amino-acid deletion in the Nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China is not related to its virulence

L Zhou, J Zhang, J Zeng, S Yin, Y Li, L Zheng… - Journal of …, 2009 - Am Soc Microbiol
During the past 2 years, an atypical clinical outbreak, caused by a highly pathogenic porcine
reproductive and respiratory syndrome virus (PRRSV) with a unique 30-amino-acid deletion …

Immunological solutions for treatment and prevention of porcine reproductive and respiratory syndrome (PRRS)

MP Murtaugh, M Genzow - Vaccine, 2011 - Elsevier
Vaccination is the principal means used to control and treat porcine reproductive and
respiratory syndrome virus (PRRSV) infection. An array of PRRS vaccine products is …

Live porcine reproductive and respiratory syndrome virus vaccines: current status and future direction

GJ Renukaradhya, XJ Meng, JG Calvert, M Roof… - Vaccine, 2015 - Elsevier
Porcine reproductive and respiratory syndrome (PRRS) caused by PRRS virus (PRRSV)
was reported in the late 1980s. PRRS still is a huge economic concern to the global pig …

Nsp9 and Nsp10 contribute to the fatal virulence of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China

Y Li, L Zhou, J Zhang, X Ge, R Zhou, H Zheng… - PLoS …, 2014 - journals.plos.org
Atypical porcine reproductive and respiratory syndrome (PRRS), which is caused by the
Chinese highly pathogenic PRRS virus (HP-PRRSV), has resulted in large economic loss to …

The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis

N Music, CA Gagnon - Animal health research reviews, 2010 - cambridge.org
Porcine reproductive and respiratory syndrome (PRRS) is an economically devastating viral
disease affecting the swine industry worldwide. The etiological agent, PRRS virus (PRRSV) …

Porcine reproductive and respiratory syndrome (PRRS): an immune dysregulatory pandemic

JE Butler, KM Lager, W Golde, KS Faaberg… - Immunologic …, 2014 - Springer
Porcine reproductive and respiratory disease syndrome (PRRS) is a viral pandemic that
especially affects neonates within the “critical window” of immunological development …

Porcine reproductive and respiratory disease virus: Evolution and recombination yields distinct ORF5 RFLP 1-7-4 viruses with individual pathogenicity

AGM van Geelen, TK Anderson, KM Lager, PB Das… - Virology, 2018 - Elsevier
Recent cases of porcine reproductive and respiratory syndrome virus (PRRSV) infection in
United States swine-herds have been associated with high mortality in piglets and severe …