Rationale: Nonadherence to inhaled corticosteroid therapy (ICS) is a major contributor to
poor control in difficult asthma, yet it is challenging to ascertain. Objectives: Identify a test for …

Background Although the efficacy of corticosteroid treatment in controlling asthma is widely
accepted, its effectiveness is undermined by poor adherence. However, the optimal method …

Asthma prevalence in Italy is on the rise and is estimated to be over 6% of the general
population. The diagnosis of asthma can be challenging and elusive, especially in children …

Rationale: Better characterization of childhood wheeze phenotypes using newer statistical
methods provides a basis for addressing the heterogeneity of childhood asthma. Outcomes …

Background. Children with asthma experience changes in functional capacity and
autonomic control. The literature suggests that this imbalance is responsible for bronchial …

Purpose Fraction of exhaled nitric oxide (FeNO) and soluble advanced glycation end-
product receptor (sRAGE) are proposed as biomarkers of asthma, therefore we sought to …

Nitric oxide (NO) is both a gas and a ubiquitous inter-and intracellular messenger with
numerous physiological functions. As its synthesis is markedly increased during …

Background Fractional exhaled nitric oxide (FENO) is increasingly being used in the office-
based management of asthma, but data in children are limited. Objectives To report FENO …

Asthma is a condition where the airways become tiny and swollen producing extra mucus.
This can cause breathing difficulty and wheezing, coughing, and shortness of breath. Self …

Background Intermittent and mild persistent asthma are defined according to symptom
frequency and spirometry and treated differently. To our knowledge, there is no study …