Multiciliated cells are epithelial cells that are in contact with bodily fluids and are required for
the proper function of major organs including the brain, the respiratory system and the …

The transient receptor potential (TRP) superfamily consists of a large number of cation
channels that are mostly permeable to both monovalent and divalent cations. The 28 …

The ion channels Piezo1 and TRPV4 have both, independently, been implicated in high
venous pressure–and fluid shear stress–induced vascular hyperpermeability in endothelial …

Cells respond to physical stimuli, such as stiffness, fluid shear stress and hydraulic
pressure,. Extracellular fluid viscosity is a key physical cue that varies under physiological …

Elevated pressure in the pancreatic gland is the central cause of pancreatitis following
abdominal trauma, surgery, endoscopic retrograde cholangiopancreatography, and …

Cell motility is central to tissue homeostasis in health and disease, and there is hardly any
cell in the body that is not motile at a given point in its life cycle. Important physiological …

Primary cilia are solitary, tiny organelles that project from the membrane of most mammalian
cells. Housing components of the cell division apparatus between cell divisions, they also …

The rheological properties of the extracellular fluid in the female reproductive tract vary
spatiotemporally, however, the effect on the behaviour of epithelial cells that line the tract is …

Recent advances in our understanding of the structure-function relationship of motile cilia
with the 9+ 2 microtubular arrangement have helped explain some of the mechanisms of …

Objective—Ca2+-influx through transient receptor potential (TRP) channels was proposed to
be important in endothelial function, although the precise role of specific TRP channels is …