Angiogenesis and anti-leukaemia activity of novel indole derivatives as potent colchicine binding site inhibitors
Y Yao, T Huang, Y Wang, L Wang, S Feng… - Journal of Enzyme …, 2022 - Taylor & Francis
The screened compound DYT-1 from our in-house library was taken as a lead (inhibiting
tubulin polymerisation: IC50= 25.6 µM, anti-angiogenesis in Zebrafish: IC50= 38.4 µM, anti …
tubulin polymerisation: IC50= 25.6 µM, anti-angiogenesis in Zebrafish: IC50= 38.4 µM, anti …
[HTML][HTML] Bone Mineral Density, C-Terminal Telopeptide of Type I Collagen, and Osteocalcin as Monitoring Parameters of Bone Remodeling in CML Patients …
Background: Chronic myeloid leukemia (CML) is one of the most commonly found types of
myeloproliferative neoplasms, characterized by increased proliferation of granulocytic cells …
myeloproliferative neoplasms, characterized by increased proliferation of granulocytic cells …
Baseline blood count levels increase odds of cytopenia among CML patients in Kenya: a case control study
Background Imatinib is the gold standard for the treatment of all phases of Philadelphia
positive Chronic Myeloid Leukemia (CML). During treatment, patients may develop …
positive Chronic Myeloid Leukemia (CML). During treatment, patients may develop …
Bone marrow niche crosses paths with BMPs: a road to protection and persistence in CML
C Busch, H Wheadon - Biochemical Society Transactions, 2019 - portlandpress.com
Chronic myeloid leukaemia (CML) is a paradigm of precision medicine, being one of the first
cancers to be treated with targeted therapy. This has revolutionised CML therapy and patient …
cancers to be treated with targeted therapy. This has revolutionised CML therapy and patient …
[PDF][PDF] Myelofibrosis in patients of chronic myeloid leukemia in chronic phase at presentation
Objective: To determine the frequency and grading of myelofibrosis in patients of chronic
myeloid leukaemia in chronic phase, and the association of cytopenias/cytosis with the …
myeloid leukaemia in chronic phase, and the association of cytopenias/cytosis with the …
Association of pre-treatment bone marrow morphology and achievement of BCR-ABL1 transcript milestones in CML
Chronic myeloid leukemia (CML) is characterized by the fusion gene BCR-ABL1 which
encodes aberrantly functioning tyrosine kinase. Treatment with tyrosine kinase inhibitors …
encodes aberrantly functioning tyrosine kinase. Treatment with tyrosine kinase inhibitors …
Evaluation of visual evoked potential in chronic myeloid leukemias
A Agrawal, S Aggarwal, R Singh… - Oman Journal of …, 2023 - journals.lww.com
BACKGROUND: Visual complaint is not very uncommon in chronic myeloid leukemia (CML)
patients. Our study aims to evaluate the visual pathway using visual evoked potential (VEP) …
patients. Our study aims to evaluate the visual pathway using visual evoked potential (VEP) …
Prognostic Impact of Bone Marrow Fibrosis and Effects of Tyrosine Kinase Inhibitors on Bone Marrow Fibrosis in Chronic Myeloid Leukemia
MS Pepeler, M Tıglıoglu, S Dagdas… - … Myeloma and Leukemia, 2024 - Elsevier
Background Myelofibrosis is reported in around 40% of newly diagnosed chronic myeloid
leukemia (CML) patients and have an important role in the pathobiology and prognosis of …
leukemia (CML) patients and have an important role in the pathobiology and prognosis of …
Diagnostic Approach to Myeloid Neoplasms Myeloid Neoplasms With Hyperproliferative Activity
ML MPN - 2024 - igi-global.com
Myeloproliferative neoplasms comprise BCR-ABL1 positive CML, Classic MPNs BCR-ABL1
negative, and a group of nonclassical MPNs. They share the common feature of …
negative, and a group of nonclassical MPNs. They share the common feature of …
[PDF][PDF] BMD, CTX-1, and Osteocalcin as Monitoring Parameters of Bone Remodelling in CML Patients Undergoing Imatinib Therapy: From Basic Science to Clinical …
N Indarwulan, M Savitri, A Ashariati, UY Bintoro… - 2024 - preprints.org
Chronic Myeloid Leukemia (CML) is one of the most commonly found types of
myeloproliferative neoplasms, characterized by increased proliferation of granulocytic cells …
myeloproliferative neoplasms, characterized by increased proliferation of granulocytic cells …