Low back pain is the leading cause for years lived in disability. Most people with acute low
back pain improve rapidly, but 4% to 25% of patients become chronic. Since the previous …

Objective To identify and quantify potential risk factors for osteoarthritis (OA) following
traumatic knee injury. Design Systematic review and meta-analyses that estimated the odds …

Clinical prediction models combine multiple predictors to estimate risk for the presence of a
particular condition (diagnostic models) or the occurrence of a certain event in the future …

Prediction models in health care use predictors to estimate for an individual the probability
that a condition or disease is already present (diagnostic model) or will occur in the future …

When designing a study to develop a new prediction model with binary or time‐to‐event
outcomes, researchers should ensure their sample size is adequate in terms of the number …

The goal of the OPTIKNEE consensus is to improve knee and overall health, to prevent
osteoarthritis (OA) after a traumatic knee injury. The consensus followed a seven-step hybrid …

Prognostic factors are associated with the risk of future health outcomes in individuals with a
particular health condition or some clinical start point (eg, a particular diagnosis). Research …

The term “precision medicine” has become very popular over recent years, fuelled by
scientific as well as political perspectives. Despite its popularity, its exact meaning, and how …

The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …

Objective The objective of this study was to provide guidance on the use of the Grading of
Recommendations Assessment, Development and Evaluation (GRADE) approach to …