In-silico formulation of a next-generation polyvalent vaccine against multiple strains of monkeypox virus and other related poxviruses

AT Moin, NA Rani, RB Patil, TB Robin, MA Ullah… - Plos one, 2024‏ - journals.plos.org
Mpox (formerly known as monkeypox) virus and some related poxviruses including smallpox
virus pose a significant threat to public health, and effective prevention and treatment …

Lactobacilli-derived adjuvants combined with immunoinformatics-driven multi-epitope antigens based approach protects against Clostridium perfringens in a mouse …

Z Guo, H Ren, Q Chang, R Liu, X Zhou, K Xue… - International Journal of …, 2024‏ - Elsevier
Clostridium perfringens is ubiquitously distributed and capable of secreting toxins, posing a
significant threat to animal health. Infections caused by Clostridium perfringens, such as …

Structural informatics approach for designing an epitope-based vaccine against the brain-eating Naegleria fowleri

A Sarfraz, TU Wara, Sheheryar, K Chen… - Frontiers in …, 2023‏ - frontiersin.org
Primary Amoebic Meningoencephalitis (PAM), a severe lethal brain disease, is caused by a
parasite, Naegleria fowleri, also known as the “brain-eating amoeba”. The chances of a …

Development of a novel multi-epitope subunit mRNA vaccine candidate to combat Acinetobacter baumannii

S Ma, F Zhu, P Zhang, Y Xu, Z Zhou, H Yang, C Tan… - Scientific Reports, 2025‏ - nature.com
Acinetobacter baumannii, an opportunistic bacterium prevalent in various environment, is a
significant cause of nosocomial infections in ICUs. As the causative agent of pneumonia …

[HTML][HTML] Understanding and addressing the global impact: A systematic review and cross-sectional bibliometric analysis of Langya henipavirus and pre-existing …

JD Li, YQ Liu, RQ He, ZG Huang, WY Huang… - Journal of Infection and …, 2024‏ - Elsevier
In 2022, Langya henipavirus was identified in patients with fever in eastern China. This
study provides an overview of the scientific landscape, highlights research focus areas, and …

Reverse vaccinology approaches to design a potent multiepitope vaccine against the HIV whole genome: immunoinformatic, bioinformatics, and molecular dynamics …

A Hashempour, N Khodadad, S Akbarinia… - BMC Infectious …, 2024‏ - Springer
Substantial advances have been made in the development of promising HIV vaccines to
eliminate HIV-1 infection. For the first time, one hundred of the most submitted HIV subtypes …

In Silico design of a multi-epitope vaccine for Human Parechovirus: Integrating immunoinformatics and computational techniques

A Sarker, MM Rahman, C Khatun, C Barai, N Roy… - PLoS …, 2024‏ - journals.plos.org
Human parechovirus (HPeV) is widely recognized as a severe viral infection affecting infants
and neonates. Belonging to the Picornaviridae family, HPeV is categorized into 19 distinct …

Advancing one health vaccination: In silico design and evaluation of a multi-epitope subunit vaccine against Nipah virus for cross-species immunization using …

EC Banico, EMJS Sira, LE Fajardo, ANG Dulay… - Plos one, 2024‏ - journals.plos.org
The resurgence of the Nipah virus (NiV) in 2023 has raised concerns for another potentially
severe pandemic, given its history of high mortality from previous outbreaks. Unfortunately …

Bioinformatics design of a peptide vaccine containing sarcoma antigen NY-SAR-35 epitopes against breast cancer and evaluation of its immunological function in …

N Samman, H Mohabatkar, M Behbahani… - Plos one, 2024‏ - journals.plos.org
The development of a cancer vaccine has become an essential focus in the field of medical
biotechnology and immunology. In our study, the NY-SAR-35 cancer/testis antigen was …

Immunoinformatics design of a multi-epitope vaccine for Chlamydia trachomatis major outer membrane proteins

S Shetty, S Dash, A Kumar, S Vishwanath, SG Kini… - Scientific Reports, 2024‏ - nature.com
Chlamydia trachomatis (CT) remains a significant infectious cause of blindness and sexually
transmitted infections worldwide. The objective and novelty of this study lie in using different …