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The role of autophagy in viral infections
T Chen, S Tu, L Ding, M **, H Chen, H Zhou - Journal of biomedical …, 2023 - Springer
Autophagy is an evolutionarily conserved catabolic cellular process that exerts antiviral
functions during a viral invasion. However, co-evolution and co-adaptation between viruses …
functions during a viral invasion. However, co-evolution and co-adaptation between viruses …
Autophagy in aging-related diseases and cancer: Principles, regulatory mechanisms and therapeutic potential
N Wu, W Zheng, Y Zhou, Y Tian, M Tang, X Feng… - Ageing Research …, 2024 - Elsevier
Macroautophagy/autophagy is primarily accountable for the degradation of damaged
organelles and toxic macromolecules in the cells. Regarding the essential function of …
organelles and toxic macromolecules in the cells. Regarding the essential function of …
Autophagy modulation as a potential therapeutic target for diverse diseases
Autophagy is an essential, conserved lysosomal degradation pathway that controls the
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …
Autophagy in immunity and inflammation
Autophagy is an essential, homeostatic process by which cells break down their own
components. Perhaps the most primordial function of this lysosomal degradation pathway is …
components. Perhaps the most primordial function of this lysosomal degradation pathway is …
The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections
Virus infection induces different cellular responses in infected cells. These include cellular
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
[HTML][HTML] Autophagy and the integrated stress response
Autophagy is a tightly regulated pathway involving the lysosomal degradation of cytoplasmic
organelles or cytosolic components. This pathway can be stimulated by multiple forms of …
organelles or cytosolic components. This pathway can be stimulated by multiple forms of …
Inflammation-induced, STING-dependent autophagy restricts Zika virus infection in the Drosophila brain
Y Liu, B Gordesky-Gold, M Leney-Greene… - Cell host & …, 2018 - cell.com
The emerging arthropod-borne flavivirus Zika virus (ZIKV) is associated with neurological
complications. Innate immunity is essential for the control of virus infection, but the innate …
complications. Innate immunity is essential for the control of virus infection, but the innate …
[HTML][HTML] Biological functions and regulatory mechanisms of hypoxia-inducible factor-1α in ischemic stroke
Q He, Y Ma, J Liu, D Zhang, J Ren, R Zhao… - Frontiers in …, 2021 - frontiersin.org
Ischemic stroke is caused by insufficient cerebrovascular blood and oxygen supply. It is a
major contributor to death or disability worldwide and has become a heavy societal and …
major contributor to death or disability worldwide and has become a heavy societal and …
Molecular biology of atherosclerosis
PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
Host immune responses to Toxoplasma gondii
Toxoplasma gondii can infect homoeothermic animals including humans and cause lethal
toxoplasmosis in immunocompromised individuals. When hosts are infected with T. gondii …
toxoplasmosis in immunocompromised individuals. When hosts are infected with T. gondii …