This review delves into the intricate relationship between anemia, iron metabolism, and
human immunodeficiency virus (HIV), aiming to unravel the interconnected pathways that …

Cancer immunotherapy using immune-checkpoint inhibitors (ICIs) has revolutionized the
field of cancer treatment; however, ICI efficacy is constrained by progressive dysfunction of …

Complex regulation of the immune response is necessary to support effective defense of an
organism against hostile invaders and to maintain tolerance to harmless microorganisms …

Haematopoiesis dysregulation with the presence of immature myeloid and erythroid
immunosuppressive cells are key characteristics of the immune escape phase of tumour …

Abstract Programmed cell death-1 (PD-1) and PD-1 ligand 1 (PD-L1) are target molecules
for immunotherapy in non-small cell lung cancer. PD-L1 is expressed not only in cancer …

Background Cutaneous squamous cell carcinoma (CSCC) is the second most common skin
cancer whose incidence is growing parallel to the lengthening of the average lifespan …

As the main cause of death in the world, cancer is one of the major health threats for
humans. In recent years, traditional Chinese medicine has gained great attention in …

Despite spectacular clinical successes across several cancer types, immune checkpoint
inhibition is effective only in subgroups of patients and suffers from significant systemic …

Abstract CD71+ erythroid cells (CECs) have been recently recognized in both neonates and
cancer patients as potent immunoregulatory cells. Here, we show that in mice early-stage …

Extracellular vesicles (EVs) exhibit pivotal functions in cancer via intercellular
communication through shuttling microRNA (miRNA) and protein. Therefore, we aim to …