Antimicrobial peptides: classification, design, application and research progress in multiple fields

Y Huan, Q Kong, H Mou, H Yi - Frontiers in microbiology, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and
they are an important part of the innate immune system of different organisms. AMPs have a …

[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era

J Wang, X Dou, J Song, Y Lyu, X Zhu… - Medicinal research …, 2019 - Wiley Online Library
Antimicrobial peptides (AMPs), critical components of the innate immune system, are widely
distributed throughout the animal and plant kingdoms. They can protect against a broad …

Silica nanoparticles—a versatile tool for the treatment of bacterial infections

V Selvarajan, S Obuobi, PLR Ee - Frontiers in Chemistry, 2020 - frontiersin.org
The rapid emergence of drug resistance continues to outpace the development of new
antibiotics in the treatment of infectious diseases. Conventional therapy is currently limited …

Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications

Y Wu, K Chen, J Wang, M Chen, Y Chen, Y She… - Progress in Polymer …, 2023 - Elsevier
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …

pH‐triggered size‐transformable and bioactivity‐switchable self‐assembling chimeric peptide nanoassemblies for combating drug‐resistant bacteria and biofilms

P Tan, C Wu, Q Tang, T Wang, C Zhou… - Advanced …, 2023 - Wiley Online Library
Drug‐resistant bacteria and biofilm‐associated infections are prominent problems in the
field of antibacterial medicine, seriously affecting human and animal health. Despite the …

Developments in Emerging Topical Drug Delivery Systems for Ocular Disorders

S Mandal, P Vishvakarma… - Current Drug Research …, 2024 - benthamdirect.com
According to the current information, using nano gels in the eyes have therapeutic benefits.
Industry growth in the pharmaceutical and healthcare sectors has been filled by …

Antimicrobial peptides as an alternative for the eradication of bacterial biofilms of multi-drug resistant bacteria

JTC Pontes, AB Toledo Borges, CA Roque-Borda… - Pharmaceutics, 2022 - mdpi.com
Bacterial resistance is an emergency public health problem worldwide, compounded by the
ability of bacteria to form biofilms, mainly in seriously ill hospitalized patients. The World …

Antimicrobial peptides with high proteolytic resistance for combating gram-negative bacteria

J Wang, J Song, Z Yang, S He, Y Yang… - Journal of medicinal …, 2019 - ACS Publications
Poor proteolytic resistance is an urgent problem to be solved in the clinical application of
antimicrobial peptides (AMPs), yet common solutions, such as complicated chemical …