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Antimicrobial resistance and COVID-19: Intersections and implications
Before the coronavirus 2019 (COVID-19) pandemic began, antimicrobial resistance (AMR)
was among the top priorities for global public health. Already a complex challenge, AMR …
was among the top priorities for global public health. Already a complex challenge, AMR …
The impact of COVID-19 on TB: a review of the data
Early in the COVID-19 pandemic, models predicted hundreds of thousands of additional TB
deaths as a result of health service disruption. To date, empirical evidence on the effects of …
deaths as a result of health service disruption. To date, empirical evidence on the effects of …
Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection
Mycobacterium tuberculosis is a leading cause of mortality worldwide and establishes a
long-lived latent infection in a substantial proportion of the human population. Multiple lines …
long-lived latent infection in a substantial proportion of the human population. Multiple lines …
Risk factors for tuberculosis
The risk of progression from exposure to the tuberculosis bacilli to the development of active
disease is a two‐stage process governed by both exogenous and endogenous risk factors …
disease is a two‐stage process governed by both exogenous and endogenous risk factors …
Drivers of tuberculosis transmission
Measuring tuberculosis transmission is exceedingly difficult, given the remarkable variability
in the timing of clinical disease after Mycobacterium tuberculosis infection; incident disease …
in the timing of clinical disease after Mycobacterium tuberculosis infection; incident disease …
Are we underestimating the annual risk of infection with Mycobacterium tuberculosis in high-burden settings?
The annual risk of infection with Mycobacterium tuberculosis determines a population's
exposure level and thus the fraction of incident tuberculosis resulting from recent infection …
exposure level and thus the fraction of incident tuberculosis resulting from recent infection …
Paediatric tuberculosis
SM Newton, AJ Brent, S Anderson… - The Lancet infectious …, 2008 - thelancet.com
Tuberculosis continues to cause an unacceptably high toll of disease and death among
children worldwide, particularly in the wake of the HIV epidemic. Increased international …
children worldwide, particularly in the wake of the HIV epidemic. Increased international …
Community-wide screening for tuberculosis in a high-prevalence setting
Abstract Background The World Health Organization has set ambitious targets for the global
elimination of tuberculosis. However, these targets will not be achieved at the current rate of …
elimination of tuberculosis. However, these targets will not be achieved at the current rate of …
Transmission of Mycobacterium Tuberculosis in Households and the Community: A Systematic Review and Meta-Analysis
L Martinez, Y Shen, E Mupere, A Kizza… - American journal of …, 2017 - academic.oup.com
The individual-and population-level impact of household tuberculosis exposure on
transmission is unclear but may have implications for the effectiveness and implementation …
transmission is unclear but may have implications for the effectiveness and implementation …
The transmission of Mycobacterium tuberculosis in high burden settings
Unacceptable levels of Mycobacterium tuberculosis transmission are noted in high burden
settings and a renewed focus on reducing person-to-person transmission in these …
settings and a renewed focus on reducing person-to-person transmission in these …