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Molecular physiology of Arc/Arg3. 1: The oligomeric state hypothesis of synaptic plasticity
MS Eriksen, CR Bramham - Acta Physiologica, 2022 - Wiley Online Library
The immediate early gene, Arc, is a pivotal regulator of synaptic plasticity, memory, and
cognitive flexibility. But what is Arc protein? How does it work? Inside the neuron, Arc is a …
cognitive flexibility. But what is Arc protein? How does it work? Inside the neuron, Arc is a …
Arc protein, a remnant of ancient retrovirus, forms virus-like particles, which are abundantly generated by neurons during epileptic seizures, and affects epileptic …
A product of the immediate early gene Arc (Activity-regulated cytoskeleton-associated
protein or Arc protein) of retroviral ancestry resides in the genome of all tetrapods for millions …
protein or Arc protein) of retroviral ancestry resides in the genome of all tetrapods for millions …
A cryo-ET survey of microtubules and intracellular compartments in mammalian axons
The neuronal axon is packed with cytoskeletal filaments, membranes, and organelles, many
of which move between the cell body and axon tip. Here, we used cryo-electron tomography …
of which move between the cell body and axon tip. Here, we used cryo-electron tomography …
Astragaloside IV mediates radiation-induced neuronal damage through activation of BDNF-TrkB signaling
X Liu, Y Ding, C Jiang, Y **n, X Ma, M Xu, Q Wang… - Phytomedicine, 2024 - Elsevier
Background Electromagnetic radiation is relevant to human life, and radiation can trigger
neurodegenerative diseases by altering the function of the central nervous system through …
neurodegenerative diseases by altering the function of the central nervous system through …
Extracellular Vesicle-Mediated Neuron–Glia Communications in the Central Nervous System
T Ikezu, Y Yang, C Verderio… - Journal of …, 2024 - jneurosci.org
Communication between neurons and glia significantly influences the development
maturation, plasticity, and disease progressions of the nervous system. As a new signaling …
maturation, plasticity, and disease progressions of the nervous system. As a new signaling …
Mechanisms and functions of activity-regulated cytoskeleton-associated protein in synaptic plasticity
Y Chen, X Wang, B **ao, Z Luo, H Long - Molecular Neurobiology, 2023 - Springer
Activity-regulated cytoskeleton-associated protein (Arc) is one of the most important
regulators of cognitive functions in the brain regions. As a hub protein, Arc plays different …
regulators of cognitive functions in the brain regions. As a hub protein, Arc plays different …
RNA‐binding proteins in pain
PR Smith, ZT Campbell - Wiley Interdisciplinary Reviews: RNA, 2024 - Wiley Online Library
RNAs are meticulously controlled by proteins. Through direct and indirect associations,
every facet in the brief life of an mRNA is subject to regulation. R NA‐b inding p roteins …
every facet in the brief life of an mRNA is subject to regulation. R NA‐b inding p roteins …
A compendium of validated pain genes
E Wistrom, R Chase, PR Smith… - WIREs Mechanisms of …, 2022 - Wiley Online Library
The development of novel pain therapeutics hinges on the identification and rigorous
validation of potential targets. Model organisms provide a means to test the involvement of …
validation of potential targets. Model organisms provide a means to test the involvement of …
Astragaloside IV ameliorates radiation‐induced nerve cell damage by activating the BDNF/TrkB signaling pathway
X Liu, Y Ding, C Jiang, X Ma, Y **n, Y Li… - Phytotherapy …, 2023 - Wiley Online Library
Radiation can induce nerve cell damage. Synapse connectivity and functionality are thought
to be the essential foundation of all cognitive functions. Therefore, treating and preventing …
to be the essential foundation of all cognitive functions. Therefore, treating and preventing …
The RNA-binding protein HuR is integral to the function of nociceptors in mice and humans
HuR is an RNA-binding protein implicated in RNA processing, stability, and translation.
Previously, we examined protein synthesis in dorsal root ganglion (DRG) neurons treated …
Previously, we examined protein synthesis in dorsal root ganglion (DRG) neurons treated …