Glioblastoma (GBM) tumor microenvironment (TME) is a highly heterogeneous and complex
system, which in addition to cancer cells, consists of various resident brain and immune cells …

Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration.
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …

Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates …

Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide and is a risk
factor for dementia later in life. Research into the pathophysiology of TBI has focused on the …

A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

Alzheimer's disease (AD) is a multifactorial neurodegenerative disease which is mainly
characterized by progressive impairment in cognition, emotion, language and memory in …

The pathway leading from soluble and monomeric to hyperphosphorylated, insoluble and
filamentous tau protein is at the centre of many human neurodegenerative diseases …