Single-molecule experiments in biological physics: methods and applications

F Ritort - Journal of Physics: Condensed Matter, 2006 - iopscience.iop.org
I review single-molecule experiments (SMEs) in biological physics. Recent technological
developments have provided the tools to design and build scientific instruments of high …

A primer on the oxDNA model of DNA: when to use it, how to simulate it and how to interpret the results

A Sengar, TE Ouldridge, O Henrich… - Frontiers in Molecular …, 2021 - frontiersin.org
The oxDNA model of Deoxyribonucleic acid has been applied widely to systems in biology,
biophysics and nanotechnology. It is currently available via two independent open source …

Nonlinear dynamics and statistical physics of DNA

M Peyrard - Nonlinearity, 2004 - iopscience.iop.org
DNA is not only an essential object of study for biologists—it also raises very interesting
questions for physicists. This paper discuss its nonlinear dynamics, its statistical mechanics …

Sequence-dependent thermodynamics of a coarse-grained DNA model

P Šulc, F Romano, TE Ouldridge, L Rovigatti… - The Journal of …, 2012 - pubs.aip.org
originally designed to reproduce the properties of DNA molecules with average sequences.
The new parametrization introduces sequence-dependent stacking and base-pairing …

Biomolecules under mechanical force

S Kumar, MS Li - Physics Reports, 2010 - Elsevier
Recent advances in single molecule experiments have raised many challenges. These
challenges can be met by a proper understanding of the inter-and intra-molecular …

Why is the DNA denaturation transition first order?

Y Kafri, D Mukamel, L Peliti - Physical Review Letters, 2000 - APS
We study a model for the denaturation transition of DNA in which the molecules are
considered as being composed of a sequence of alternating bound segments and …

Force and kinetic barriers to unzip** of the DNA double helix

S Cocco, R Monasson… - Proceedings of the …, 2001 - National Acad Sciences
A theory of the unzip** of double-stranded DNA is presented and is compared to recent
micromanipulation experiments. It is shown that the interactions that stabilize the double …

Thermal denaturation of a helicoidal DNA model

M Barbi, S Lepri, M Peyrard, N Theodorakopoulos - Physical Review E, 2003 - APS
We study the static and dynamical properties of DNA in the vicinity of its melting transition, ie,
the separation of the two strands upon heating. The investigation is based on a simple …

Structural transitions in DNA driven by external force and torque

A Sarkar, JF Leger, D Chatenay, JF Marko - Physical Review E, 2001 - APS
Experiments on single DNA molecules have shown that abrupt transitions between states of
different extensions can be driven by stretching and twisting. Here we show how a simple …

Simple model for the DNA denaturation transition

MS Causo, B Coluzzi, P Grassberger - Physical Review E, 2000 - APS
We study pairs of interacting self-avoiding walks {ω 1, ω 2} on the 3 d simple cubic lattice.
They have a common origin ω 0 1= ω 0 2, and are allowed to overlap only at the same …