Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain
H Seki, S Pellett, P Šilhár, GN Stowe, B Blanco… - Bioorganic & Medicinal …, 2014 - Elsevier
Abstract Botulinum neurotoxin A (BoNT/A) is the most potent toxin known. Unfortunately, it is
also a potential bioweapon in terrorism, which is without an approved therapeutic treatment …
also a potential bioweapon in terrorism, which is without an approved therapeutic treatment …
1-Propanephosphonic acid cyclic anhydride (T3P) as an efficient promoter for the Lossen rearrangement: application to the synthesis of urea and carbamate …
The synthesis of hydroxamic acids starting from carboxylic acids employing 1-
propanephosphonic acid cyclic anhydride (T3P) activation is described. Application of …
propanephosphonic acid cyclic anhydride (T3P) activation is described. Application of …
Organic isocyanates and isothiocyanates: versatile intermediates in agrochemistry
C Lamberth - Synthesis, 2022 - thieme-connect.com
In recent decades, organic isocyanates and isothiocyanates have been often applied as
reactive intermediates in research syntheses or manufacturing routes of many …
reactive intermediates in research syntheses or manufacturing routes of many …
Iodine-mediated oxidative coupling of hydroxamic acids with amines towards a new peptide-bond formation
M Krishnamurthy, TM Vishwanatha, NR Panguluri… - Synlett, 2015 - thieme-connect.com
An efficient and straightforward approach for the coupling of N α-protected hydroxamic acids
with an amino component in the presence of iodine is delineated. The reaction is mediated …
with an amino component in the presence of iodine is delineated. The reaction is mediated …
Improved Synthesis of Unsymmetrical Ureas via Carbamates
R Prachi, DK Tanwar, MS Gill - SynOpen, 2023 - thieme-connect.com
An efficient, cost-effective, easy and green method is reported for the preparation of N, N′-
alkyl aryl ureas and N, N′-dialkylureas via carbamates. This improved procedure is devoid …
alkyl aryl ureas and N, N′-dialkylureas via carbamates. This improved procedure is devoid …
Synthesis of New Dialkyl 2, 2′-[Carbonylbis (azanediyl)] dibenzoates via Curtius Rearrangement
H Yassine, J Bouali, A Oumessaoud, S Hamri… - …, 2021 - thieme-connect.com
The 2-(alkylcarbonyl) benzoic acids obtained by esterification of phthalic anhydride are
converted into azide derivatives: alkyl 2-[(azidocarbonyl) amino] benzoates and to ureas …
converted into azide derivatives: alkyl 2-[(azidocarbonyl) amino] benzoates and to ureas …
N, N′-carbonyldiimidazole-mediated dbu-catalyzed one-pot synthesis of urea-tethered glycosyl amino acids and glycoconjugates
VV Sureshbabu - Synlett, 2011 - thieme-connect.com
An efficient, mild, simple, and alternative one-pot protocol for the synthesis of urea-tethered
glycosyl amino acids mediated by N, N′-carbonyldiimidazole employing DBU as a catalyst …
glycosyl amino acids mediated by N, N′-carbonyldiimidazole employing DBU as a catalyst …
[PDF][PDF] НОВЫЙ СИНТЕЗ ВЫСОКОСЕЛЕКТИВНОГО ИНГИБИТОРА ГИСТОНДЕАЦЕТИЛАЗЫ 6 N-ГИДРОКСИ-4-(2-МЕТИЛ-1,2,3,4-ТЕТРАГИДРОПИРИДО[4,3] …
МВ Козлов, АА Клейменова… - Биоорганическая …, 2013 - researchgate.net
Семейство гистондеацетилаз человека (КФ 3.5. 1.17; HDAC) включает в себя 11
ферментов, которые разделены на четыре класса (I, IIа, IIb и IV)[1]. Эти ферменты …
ферментов, которые разделены на четыре класса (I, IIа, IIb и IV)[1]. Эти ферменты …