The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders

WL Miller, RJ Auchus - Endocrine reviews, 2011‏ - academic.oup.com
Steroidogenesis, the processes by which cholesterol is converted to steroid hormones,
involves transport proteins, enzymes, redox partners and cofactors. Most steroidogenic …

[HTML][HTML] Early steps in steroidogenesis: intracellular cholesterol trafficking: thematic review series: genetics of human lipid diseases

WL Miller, HS Bose - Journal of lipid research, 2011‏ - Elsevier
Steroid hormones are made from cholesterol, primarily derived from lipoproteins that enter
cells via receptor-mediated endocytosis. In endo-lysosomes, cholesterol is released from …

Molecular biology of steroid hormone synthesis

WL Miller - Endocrine reviews, 1988‏ - academic.oup.com
Introduction S TEROID hormones are familiar clinically and physiologically as regulators of
physiological processes. Five groups of steroid hormones are generally recognized …

Steroidogenic enzymes: structure, function, and role in regulation of steroid hormone biosynthesis

I Hanukoglu - The Journal of steroid biochemistry and molecular …, 1992‏ - Elsevier
In the pathways of steroid hormone biosynthesis there are two major types of enzymes:
cytochromes P450 and other steroid oxidoreductases. This review presents an overview of …

Disorders in the initial steps of steroid hormone synthesis

WL Miller - The Journal of steroid biochemistry and molecular …, 2017‏ - Elsevier
Steroidogenesis begins with cellular internalization of low-density lipoprotein particles and
subsequent intracellular processing of cholesterol. Disorders in these steps include …

[کتاب][B] Sperling pediatric endocrinology E-Book

MA Sperling - 2020‏ - books.google.com
An ideal resource for both pediatricians and endocrinologists, Sperling's Pediatric
Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new …

Leydig cells: endocrine, paracrine, and autocrine regulation

JM Saez - Endocrine reviews, 1994‏ - academic.oup.com
THAT the testes are related to the sexual characteristics of the individual and have
reproductive power was observed at an early time in history. One of the earliest descriptions …

Disorders of steroid 11β-hydroxylase isozymes

PC White, KM Curnow, L Pascoe - Endocrine reviews, 1994‏ - academic.oup.com
IT WAS first demonstrated in 1929 that extracts of adrenal glands could indefinitely sustain
patients with Addison's disease (1). During the following decade a number of steroids were …

Transcriptional regulation of steroidogenic genes: STARD1, CYP11A1 and HSD3B

HA LaVoie, SR King - Experimental biology and medicine, 2009‏ - journals.sagepub.com
Expression of the genes that mediate the first steps in steroidogenesis, the steroidogenic
acute regulatory protein (STARD1), the cholesterol side-chain cleavage enzyme …

Minireview: regulation of steroidogenesis by electron transfer

WL Miller - Endocrinology, 2005‏ - academic.oup.com
Cytochrome P450 enzymes catalyze the degradation of drugs and xenobiotics, but also
catalyze a wide variety of biosynthetic processes, including most steps in steroidogenesis …