Flavonols and flavones as potential anti‐inflammatory, antioxidant, and antibacterial compounds

MSS Chagas, MD Behrens… - Oxidative medicine …, 2022 - Wiley Online Library
Plant preparations have been used to treat various diseases and discussed for centuries.
Research has advanced to discover and identify the plant components with beneficial effects …

Flavonoids as potential anti-inflammatory molecules: A review

JM Al-Khayri, GR Sahana, P Nagella, BV Joseph… - Molecules, 2022 - mdpi.com
Hydroxylated polyphenols, also called flavonoids, are richly present in vegetables, fruits,
cereals, nuts, herbs, seeds, stems, and flowers of numerous plants. They possess numerous …

Cryopreservation of bioflavonoid-rich plant sources and bioflavonoid-microcapsules: emerging technologies for preserving bioactivity and enhancing nutraceutical …

J **ang, R Mlambo, I Shaw, Y Seid, H Shah, Y He… - Frontiers in …, 2023 - frontiersin.org
Bioflavonoids are natural polyphenolic secondary metabolites that are medicinal. These
compounds possess antitumor, cardioprotective, anti-inflammatory, antimicrobial, antiviral …

[HTML][HTML] Flavonoids against the SARS-CoV-2 induced inflammatory storm

A Liskova, M Samec, L Koklesova, SM Samuel… - Biomedicine & …, 2021 - Elsevier
The disease severity of COVID-19, especially in the elderly and patients with co-morbidities,
is characterized by hypercytokinemia, an exaggerated immune response associated with an …

Unique roles in health promotion of dietary flavonoids through gut microbiota regulation: Current understanding and future perspectives

Z Li, Z Ren, L Zhao, L Chen, Y Yu, D Wang, X Mao… - Food Chemistry, 2023 - Elsevier
Advances in understanding the biological effects of dietary flavonoids and flavonoid-rich
foods have been reported. Improving knowledge about their beneficial effects, and …

Flavonoids: structure–function and mechanisms of action and opportunities for drug development

S Safe, A Jayaraman, RS Chapkin, M Howard… - Toxicological …, 2021 - Springer
Flavonoids are polyphenolic phytochemicals produced in fruits, nuts and vegetables and
dietary consumption of these structurally diverse compounds is associated with multiple …

Pharmacological effects of polyphenol phytochemicals on the intestinal inflammation via targeting TLR4/NF-κB signaling pathway

C Yu, D Wang, Z Yang, T Wang - International journal of molecular …, 2022 - mdpi.com
TLR4/NF-κB is a key inflammatory signaling transduction pathway, closely involved in cell
differentiation, proliferation, apoptosis, and pro-inflammatory response. Toll like receptor 4 …

Rutin: A Potential Antiviral for Repurposing as a SARS-CoV-2 Main Protease (Mpro) Inhibitor

PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Various computational studies, including in silico ones, have identified several existing
compounds that could serve as effective inhibitors of the SARS-CoV-2 main protease …

[HTML][HTML] Antioxidant and anti-inflammatory effects of hesperidin methyl chalcone in experimental ulcerative colitis

CFS Guazelli, V Fattori, CR Ferraz, SM Borghi… - Chemico-biological …, 2021 - Elsevier
Neutrophil infiltration, pro-inflammatory cytokines, and reactive oxygen species (ROS)
production have been implicated in development and progression of ulcerative colitis (UC) …

Intervertebral disc degeneration and how it leads to low back pain

AD Diwan, J Melrose - Jor Spine, 2023 - Wiley Online Library
The purpose of this review was to evaluate data generated by animal models of
intervertebral disc (IVD) degeneration published in the last decade and show how this has …