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The application of Aptamer in biomarker discovery
Y Li, WW Tam, Y Yu, Z Zhuo, Z Xue, C Tsang, X Qiao… - Biomarker …, 2023 - Springer
Biomarkers are detectable molecules that can reflect specific physiological states of cells,
organs, and organisms and therefore be regarded as indicators for specific diseases. And …
organs, and organisms and therefore be regarded as indicators for specific diseases. And …
Research progress in the molecular mechanisms, therapeutic targets, and drug development of idiopathic pulmonary fibrosis
H Ma, X Wu, Y Li, Y ** spatially resolved transcriptomes in human and mouse pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis and
limited treatment options. Efforts to identify effective treatments are thwarted by limited …
limited treatment options. Efforts to identify effective treatments are thwarted by limited …
H3K18 lactylation promotes the progression of arsenite-related idiopathic pulmonary fibrosis via YTHDF1/m6A/NREP
P Wang, D **e, T **ao, C Cheng, D Wang, J Sun… - Journal of Hazardous …, 2024 - Elsevier
As epigenetic modifications, lactylation and N6-methyladenosine (m6A) have attracted wide
attention. Arsenite is an environmental pollutant that has been proven to induce idiopathic …
attention. Arsenite is an environmental pollutant that has been proven to induce idiopathic …
ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling
J Liu, Z Wu, Y Liu, Z Zhan, L Yang, C Wang… - Journal of …, 2022 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic disease with
pathophysiological characteristics of transforming growth factor-β (TGF-β), and reactive …
pathophysiological characteristics of transforming growth factor-β (TGF-β), and reactive …
Nintedanib ameliorates bleomycin-induced pulmonary fibrosis, inflammation, apoptosis, and oxidative stress by modulating PI3K/Akt/mTOR pathway in mice
L Pan, Y Cheng, W Yang, X Wu, H Zhu, M Hu, Y Zhang… - Inflammation, 2023 - Springer
Idiopathic pulmonary fibrosis (IPF) seriously threatens human life and health, and no
curative therapy is available at present. Nintedanib is the first agent approved by the US …
curative therapy is available at present. Nintedanib is the first agent approved by the US …
[HTML][HTML] The impact of formaldehyde exposure on lung inflammatory disorders: insights into asthma, bronchitis, and pulmonary fibrosis
Lung inflammatory disorders are a major global health burden, impacting millions of people
and raising rates of morbidity and death across many demographic groups. An industrial …
and raising rates of morbidity and death across many demographic groups. An industrial …
Inhaled lipid nanoparticles alleviate established pulmonary fibrosis
Pulmonary fibrosis, a sequela of lung injury resulting from severe infection such as severe
acute respiratory syndrome‐like coronavirus (SARS‐CoV‐2) infection, is a kind of life …
acute respiratory syndrome‐like coronavirus (SARS‐CoV‐2) infection, is a kind of life …
Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis
Progressive lung fibrosis is associated with poorly understood aging-related endothelial cell
dysfunction. To gain insight into endothelial cell alterations in lung fibrosis we performed …
dysfunction. To gain insight into endothelial cell alterations in lung fibrosis we performed …
Lactylation: novel epigenetic regulatory and therapeutic opportunities
H Fan, F Yang, Z **ao, H Luo, H Chen… - American Journal …, 2023 - journals.physiology.org
Lactate, which is an end product of glycolysis, has traditionally been considered a metabolic
waste. However, numerous studies have demonstrated that lactate serves metabolic and …
waste. However, numerous studies have demonstrated that lactate serves metabolic and …