Multiple roles for HIV broadly neutralizing antibodies
BF Haynes, DR Burton, JR Mascola - Science translational medicine, 2019 - science.org
Multiple roles for HIV broadly neutralizing antibodies | Science Translational Medicine news
careers commentary Journals Science Science brought to you byGoogle Indexer Log in science …
careers commentary Journals Science Science brought to you byGoogle Indexer Log in science …
Clinical trials of broadly neutralizing monoclonal antibodies for human immunodeficiency virus prevention: a review
S Mahomed, N Garrett, C Baxter… - The Journal of …, 2021 - academic.oup.com
Passive immunization with broadly neutralizing antibodies (bnAbs) is a promising approach
to reduce the 1.7 million annual human immunodeficiency virus (HIV) infections globally …
to reduce the 1.7 million annual human immunodeficiency virus (HIV) infections globally …
SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19
J Wu, B Liang, C Chen, H Wang, Y Fang… - Nature …, 2021 - nature.com
Long-term antibody responses and neutralizing activities in response to SARS-CoV-2
infection are not yet clear. Here we quantify immunoglobulin M (IgM) and G (IgG) antibodies …
infection are not yet clear. Here we quantify immunoglobulin M (IgM) and G (IgG) antibodies …
[HTML][HTML] Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer
Human cytomegalovirus (HCMV) can cause severe diseases in fetuses, newborns, and
immunocompromised individuals. Currently, no vaccines are approved, and treatment …
immunocompromised individuals. Currently, no vaccines are approved, and treatment …
Probabilities of develo** HIV-1 bNAb sequence features in uninfected and chronically infected individuals
C Kreer, C Lupo, MS Ercanoglu, L Gieselmann… - Nature …, 2023 - nature.com
HIV-1 broadly neutralizing antibodies (bNAbs) are able to suppress viremia and prevent
infection. Their induction by vaccination is therefore a major goal. However, in contrast to …
infection. Their induction by vaccination is therefore a major goal. However, in contrast to …
Influence of glycosylation on the immunogenicity and antigenicity of viral immunogens
A key aspect of successful viral vaccine design is the elicitation of neutralizing antibodies
targeting viral attachment and fusion glycoproteins that embellish viral particles. This …
targeting viral attachment and fusion glycoproteins that embellish viral particles. This …
[HTML][HTML] Next-generation bNAbs for HIV-1 cure strategies
Despite the ability to suppress viral replication using anti-retroviral therapy (ART), HIV-1
remains a global public health problem. Curative strategies for HIV-1 have to target and …
remains a global public health problem. Curative strategies for HIV-1 have to target and …
Map** the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates
The induction of broad and potent immunity by vaccines is the key focus of research efforts
aimed at protecting against HIV-1 infection. Soluble native-like HIV-1 envelope …
aimed at protecting against HIV-1 infection. Soluble native-like HIV-1 envelope …
Dynamics and durability of HIV-1 neutralization are determined by viral replication
Human immunodeficiency virus type 1 (HIV-1)-neutralizing antibodies (nAbs) that prevent
infection are the main goal of HIV vaccine discovery. But as no nAb-eliciting vaccines are yet …
infection are the main goal of HIV vaccine discovery. But as no nAb-eliciting vaccines are yet …
B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models
Animal models of human antigen-specific B cell receptors (BCRs) generally depend on
“inferred germline” sequences, and thus their relationship to authentic naive human B cell …
“inferred germline” sequences, and thus their relationship to authentic naive human B cell …