Marine cyclic peptides: Antimicrobial activity and synthetic strategies
R Ribeiro, E Pinto, C Fernandes, E Sousa - Marine Drugs, 2022 - mdpi.com
Oceans are a rich source of structurally unique bioactive compounds from the perspective of
potential therapeutic agents. Marine peptides are a particularly interesting group of …
potential therapeutic agents. Marine peptides are a particularly interesting group of …
Natural products from thioester reductase containing biosynthetic pathways
Covering: up to 2018 Thioester reductase domains catalyze two-and four-electron
reductions to release natural products following assembly on nonribosomal peptide …
reductions to release natural products following assembly on nonribosomal peptide …
[HTML][HTML] MLACP: machine-learning-based prediction of anticancer peptides
Cancer is the second leading cause of death globally, and use of therapeutic peptides to
target and kill cancer cells has received considerable attention in recent years. Identification …
target and kill cancer cells has received considerable attention in recent years. Identification …
iBCE-EL: a new ensemble learning framework for improved linear B-cell epitope prediction
Identification of B-cell epitopes (BCEs) is a fundamental step for epitope-based vaccine
development, antibody production, and disease prevention and diagnosis. Due to the …
development, antibody production, and disease prevention and diagnosis. Due to the …
AIPpred: sequence-based prediction of anti-inflammatory peptides using random forest
The use of therapeutic peptides in various inflammatory diseases and autoimmune
disorders has received considerable attention; however, the identification of anti …
disorders has received considerable attention; however, the identification of anti …
PVP-SVM: sequence-based prediction of phage virion proteins using a support vector machine
Accurately identifying bacteriophage virion proteins from uncharacterized sequences is
important to understand interactions between the phage and its host bacteria in order to …
important to understand interactions between the phage and its host bacteria in order to …
PIP-EL: a new ensemble learning method for improved proinflammatory peptide predictions
Proinflammatory cytokines have the capacity to increase inflammatory reaction and play a
central role in first line of defence against invading pathogens. Proinflammatory inducing …
central role in first line of defence against invading pathogens. Proinflammatory inducing …
DHSpred: support-vector-machine-based human DNase I hypersensitive sites prediction using the optimal features selected by random forest
DNase I hypersensitive sites (DHSs) are genomic regions that provide important information
regarding the presence of transcriptional regulatory elements and the state of chromatin …
regarding the presence of transcriptional regulatory elements and the state of chromatin …
Acremopeptaibols A–F, 16-Residue Peptaibols from the Sponge-Derived Acremonium sp. IMB18-086 Cultivated with Heat-Killed Pseudomonas aeruginosa
X Hao, S Li, J Ni, G Wang, F Li, Q Li… - Journal of Natural …, 2021 - ACS Publications
Six new 16-residue peptaibols, acremopeptaibols A–F (1–6), along with five known
compounds, were isolated from the cultures of the sponge-associated fungus Acremonium …
compounds, were isolated from the cultures of the sponge-associated fungus Acremonium …
Pentadecaibins I–V: 15-Residue Peptaibols Produced by a Marine-Derived Trichoderma sp. of the Harzianum Clade
AI Van Bohemen, N Ruiz… - Journal of Natural …, 2021 - ACS Publications
In the course of investigations on peptaibol chemodiversity from marine-derived
Trichoderma spp., five new 15-residue peptaibols named pentadecaibins I–V (1–5) were …
Trichoderma spp., five new 15-residue peptaibols named pentadecaibins I–V (1–5) were …