DNA origami

S Dey, C Fan, KV Gothelf, J Li, C Lin, L Liu… - Nature Reviews …, 2021 - nature.com
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications

Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …

Technology insight: Plant-derived vesicles—How far from the clinical biotherapeutics and therapeutic drug carriers?

M Cong, S Tan, S Li, L Gao, L Huang, HG Zhang… - Advanced drug delivery …, 2022 - Elsevier
Within the past decades, extracellular vesicles (EVs) have emerged as important mediators
of intercellular communication in both prokaryotes and higher eukaryotes to regulate a …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

Super-resolution microscopy with DNA-PAINT

J Schnitzbauer, MT Strauss, T Schlichthaerle… - Nature protocols, 2017 - nature.com
Super-resolution techniques have begun to transform biological and biomedical research by
allowing researchers to observe structures well below the classic diffraction limit of light …

Fractal assembly of micrometre-scale DNA origami arrays with arbitrary patterns

G Tikhomirov, P Petersen, L Qian - Nature, 2017 - nature.com
Self-assembled DNA nanostructures enable nanometre-precise patterning that can be used
to create programmable molecular machines,,,, and arrays of functional materials,,. DNA …

Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

N Ponnuswamy, MMC Bastings, B Nathwani… - Nature …, 2017 - nature.com
DNA nanostructures have evoked great interest as potential therapeutics and diagnostics
due to ease and robustness of programming their shapes, site-specific functionalizations …