Innovative technical solutions to realize optical biosensors with improved performance are
continuously proposed. Progress in material fabrication enables develo** novel …

The importance of microarrays in diagnostics and medicine has drastically increased in the
last few years. Nevertheless, the efficiency of a microarray-based assay intrinsically …

Due to the technical challenges of small binding aptamer development, reliable
computational simulation studies can be considered as effective tools to design novel and …

Despite the continuous advancements in bio-molecular detection and fluidic systems
integration, the realization of portable and high performance devices for diagnostic …

Microfluidic techniques are widely applied in biomolecular analysis and disease diagnostic
assays. While the volume of the sample that is directly used in such assays is often only …

Sandwich ELISA methods have been widely used for biomarker and pathogen detection
because of their high specificity and sensitivity. However, the main drawbacks of this assay …

Hybridization of complementary single strands of DNA represents a very effective natural
molecular recognition process widely exploited for diagnostic, biotechnology, and …

In this paper, we report on the postpolymerization modification (PPM) of a polymer to
introduce new functionalities that enable click chemistry reactions for microarray …

Rapid detection of whole virus particles in biological or environmental samples represents
an unmet need for the containment of infectious diseases. Here, an optical device enabling …

Binding gene-wide single-stranded nucleic acids to surface-immobilized complementary
probes is an important but challenging process for biophysical studies and diagnostic …