Quercetin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and activation of JAK2/STAT3 pathway: a target based networking pharmacology …

D Wang, F Ali, H Liu, Y Cheng, M Wu… - Frontiers in …, 2022‏ - frontiersin.org
The rapid growth of vascular smooth muscle cells (VSMCs) represents crucial pathological
changes during the development of hypertensive vascular remodeling. Although quercetin …

Echocardiography in arterial hypertension

G de Simone, C Mancusi, R Esposito… - High Blood Pressure & …, 2018‏ - Springer
Hypertension is a condition characterized by pressure and/or volume overloads and
echocardiography is helpful and feasible to understand hemodynamic mechanisms …

Variation in normal range thyroid function affects serum cholesterol levels, blood pressure, and type 2 diabetes risk: a mendelian randomization study

A Kuś, E Marouli, F Del Greco M, L Chaker… - Thyroid, 2021‏ - liebertpub.com
Background: Observational studies have demonstrated that variation in normal range thyroid
function is associated with major cardiovascular risk factors, including dyslipidemia …

Long-lasting control of LDL cholesterol induces a 40% reduction in the incidence of cardiovascular events: New insights from a 7-year study

V Trimarco, R Izzo, P Gallo, MV Manzi, I Forzano… - The Journal of …, 2024‏ - Elsevier
Recent studies have yielded controversial results on the long-term effects of statins on the
risk of cardiovascular (CV) events. To fill this knowledge gap, we assessed the relationship …

Aortic distensibility measured by automated analysis of magnetic resonance imaging predicts adverse cardiovascular events in UK biobank

M Cecelja, B Ruijsink, E Puyol‐Antón, Y Li… - Journal of the …, 2022‏ - ahajournals.org
Background Automated analysis of cardiovascular magnetic resonance images provides the
potential to assess aortic distensibility in large populations. The aim of this study was to …

The Effect of Sex on the Risk of Long-COVID and Cardiovascular Complications in Healthy Patients without Comorbidities: Data from a Polish Long-COVID …

A Bielecka-Dabrowa, A Sakowicz… - Journal of Clinical …, 2024‏ - mdpi.com
Background: The prevalence of long-COVID (LC) presents a significant challenge to
healthcare systems globally. There are still some discrepancies on the role of sex as an …

LIMK (LIM Kinase) inhibition prevents vasoconstriction-and hypertension-induced arterial stiffening and remodeling

M Morales-Quinones, FI Ramirez-Perez, CA Foote… - …, 2020‏ - ahajournals.org
Increased arterial stiffness and vascular remodeling precede and are consequences of
hypertension. They also contribute to the development and progression of life-threatening …

Characteristics of hypertension and arterial stiffness in obstructive sleep apnea: a Scandinavian experience from a prospective study of 6408 normotensive and …

S Saeed, A Romarheim, G Mancia… - The Journal of …, 2022‏ - Wiley Online Library
The impact of obstructive sleep apnea (OSA) on arterial stiffness is less studied. We aimed
to investigate the prevalence and covariates of increased pulse pressure (PP), a surrogate …

Left atrial dilatation: A target organ damage in young to middle-age hypertensive patients. The Campania Salute Network

C Mancusi, G Canciello, R Izzo, S Damiano… - International Journal of …, 2018‏ - Elsevier
Background Left atrial (LA) volume is a predictor of outcome in hypertension. It is unclear
whether or not this effect depends on coexisting target organ damage (TOD). Purpose To …

Network pharmacology identifies the mechanisms of action of TaohongSiwu decoction against essential hypertension

T Liu, W Chen, X Chen, Q Liang, W Tao… - … Medical Journal of …, 2020‏ - pmc.ncbi.nlm.nih.gov
Background TaohongSiwu decoction (THSWT), a traditional herbal formula, has been used
to treat cardiovascular and cerebrovascular diseases such as essential hypertension (EH) in …