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A narrative review on the mechanism of natural flavonoids in improving glucolipid metabolism disorders
W Niu, Y Feng, M Peng, J Cai - Phytotherapy Research, 2024 - Wiley Online Library
Glucolipid metabolism disorder (GLMD) is a complex chronic disease characterized by
glucose and lipid metabolism disorders with a complex and diverse etiology and rapidly …
glucose and lipid metabolism disorders with a complex and diverse etiology and rapidly …
Mechanisms of food-derived bioactive compounds inhibiting TLR4 activation and regulating TLR4-mediated inflammation: A comprehensive review and future …
S **ao, W Li, P Zhang, G Zhang, H Lin, X Hu - Food Bioscience, 2024 - Elsevier
In cases where inflammation is excessively activated, it can lead to autoimmune diseases,
causing significant damage to the body. Food-derived bioactive compounds (FBACs) have …
causing significant damage to the body. Food-derived bioactive compounds (FBACs) have …
Preparation, characterization, and pharmacological application of oral Honokiol-loaded solid lipid nanoparticles for diabetic neuropathy
Honokiol is a phytochemical component with a variety of pharmacological properties.
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …
However, the major limitation of Honokiol is its poor solubility and low oral bioavailability. In …
Anti-neuropathic pain activity of Ajugarin-I via activation of Nrf2 signaling and inhibition of TRPV1/TRPM8 nociceptors in STZ-induced diabetic neuropathy
This study aimed to investigate the anti-neuropathic pain activity and its underlying
molecular mechanism of Ajugarin-I (Aju-I) in a rat model of diabetic neuropathic pain. The …
molecular mechanism of Ajugarin-I (Aju-I) in a rat model of diabetic neuropathic pain. The …
Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats
H Javrushyan, E Nadiryan, A Grigoryan… - Experimental and …, 2022 - Elsevier
Background A decrease in nitric oxide (NO) bioavailability has been shown to cause
hyperglycemia, type II diabetes mellitus (DM), and chronic cardio-metabolic complications …
hyperglycemia, type II diabetes mellitus (DM), and chronic cardio-metabolic complications …
Regulation of Oxidative Stress and Apoptosis in Streptozotocin‐Induced Diabetic Rats by Egyptian Sidr Honey
B El‐Aarag, SB Shehata, IM El‐Garawani… - Chemistry & …, 2024 - Wiley Online Library
Diabetes mellitus is a global health issue characterized by hyperglycemia which leads over
time to severe damage to numerous tissues. The present study aimed to estimate the effect …
time to severe damage to numerous tissues. The present study aimed to estimate the effect …
Chrysin loaded nanovesicles ameliorated diabetic peripheral neuropathy. Role of NGF/AKT/GSK-3β pathway
SA El-Marasy, MM AbouSamra… - Chemico-Biological …, 2023 - Elsevier
Diabetic peripheral neuropathy (DPN) is a common diabetic complication. Chrysin (CHY)
has many biological properties but poor oral bioavailability. This study investigates the effect …
has many biological properties but poor oral bioavailability. This study investigates the effect …
Exploring the therapeutic potential of royal jelly in metabolic disorders and gastrointestinal diseases
HR El-Seedi, S Salama, AAA El-Wahed, Z Guo… - Nutrients, 2024 - mdpi.com
Metabolic disorders, encompassing diabetes mellitus, cardiovascular diseases,
gastrointestinal disorders, etc., pose a substantial global health threat, with rising morbidity …
gastrointestinal disorders, etc., pose a substantial global health threat, with rising morbidity …
Hyaluronate functionalized Span-Labrasol nanovesicular transdermal therapeutic system of ferulic acid targeting diabetic nephropathy
H Elmotasem, AAA Salama, ES Shalaby - International Journal of …, 2024 - Elsevier
Diabetic kidney disease, known as diabetic nephropathy (DN), is a widespread severe
diabetes complication leading to kidney failure. Due to the lack of efficacious therapies, this …
diabetes complication leading to kidney failure. Due to the lack of efficacious therapies, this …
Chrysin-based supramolecular cyclodextrin-calixarene drug delivery system: a novel approach for attenuating cardiac fibrosis in chronic diabetes
Introduction: Cardiac fibrosis is strongly induced by diabetic conditions. Both chrysin (CHR)
and calixarene OTX008, a specific inhibitor of galectin 1 (Gal-1), seem able to reduce …
and calixarene OTX008, a specific inhibitor of galectin 1 (Gal-1), seem able to reduce …