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Effect of exosomal miRNA on cancer biology and clinical applications
Z Sun, K Shi, S Yang, J Liu, Q Zhou, G Wang, J Song… - Molecular cancer, 2018 - Springer
Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely
present in various body fluids. Recently, microRNAs (miRNAs) have been identified in …
present in various body fluids. Recently, microRNAs (miRNAs) have been identified in …
MicroRNAs: biomarkers, diagnostics, and therapeutics
W Huang - Bioinformatics in MicroRNA research, 2017 - Springer
MicroRNAs (miRNAs) are small noncoding RNAs (21–23 nucleotides in length) that regulate
gene expression at translational or posttranslational levels. The major regulatory …
gene expression at translational or posttranslational levels. The major regulatory …
Natural killer–derived exosomal miR-186 inhibits neuroblastoma growth and immune escape mechanisms
In neuroblastoma, the interplay between immune cells of the tumor microenvironment and
cancer cells contributes to immune escape mechanisms and drug resistance. In this study …
cancer cells contributes to immune escape mechanisms and drug resistance. In this study …
Evaluation of circulating small extracellular vesicles derived miRNAs as biomarkers of early colon cancer: a comparison with plasma total miRNAs
Early diagnosis of colon cancer (CC) is clinically important, as it can significantly improve
patients' survival rate and quality of life. Although the potential role for small extracellular …
patients' survival rate and quality of life. Although the potential role for small extracellular …
Recent trends in targeting miRNAs for cancer therapy
Objectives MicroRNAs (miRNAs) are a type of small noncoding RNA employed by the cells
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …
MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics
A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …
remaining incurable with a median survival time of only 15 months. In an effort to identify …
A serum microRNA signature predicts tumor relapse and survival in triple-negative breast cancer patients
K Kleivi Sahlberg, G Bottai, B Naume… - Clinical cancer …, 2015 - aacrjournals.org
Purpose: Triple-negative breast cancers (TNBC) are associated with high risk of early tumor
recurrence and poor outcome. Common prognostic biomarkers give very restricted …
recurrence and poor outcome. Common prognostic biomarkers give very restricted …
The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells
Objective Ovarian cancer is the deadliest gynaecological cancer. A major contributor to the
poor survival rate is the development of chemoresistance to platinum-based therapies such …
poor survival rate is the development of chemoresistance to platinum-based therapies such …
[HTML][HTML] The role of exosomal microRNAs in the tumor microenvironment of breast cancer
Q Liu, F Peng, J Chen - International journal of molecular sciences, 2019 - mdpi.com
Breast cancer, ranking first among women's cancers worldwide, develops from the breast
tissue. Study of the breast tissue is, therefore of great significance to the diagnosis and …
tissue. Study of the breast tissue is, therefore of great significance to the diagnosis and …
Exosomal miRNA-107 induces myeloid-derived suppressor cell expansion in gastric cancer
WH Ren, XR Zhang, WB Li, Q Feng… - Cancer management …, 2019 - Taylor & Francis
Background: Myeloid-derived suppressor cells (MDSCs) promote immunosuppression in the
tumor microenvironment, support tumor growth and survival, and may contribute to …
tumor microenvironment, support tumor growth and survival, and may contribute to …