Global antimicrobial resistance in Gram-negative pathogens and clinical need
U Theuretzbacher - Current opinion in microbiology, 2017 - Elsevier
Highlights•Carbapenem-resistant Gram-negative pathogens are a priority for R&D,
according to WHO.•Increasing need for new therapies against Klebsiella, Pseudomonas and …
according to WHO.•Increasing need for new therapies against Klebsiella, Pseudomonas and …
The Global and Regional Prevalence of Hospital-Acquired Carbapenem-Resistant Klebsiella pneumoniae Infection: A Systematic Review and Meta-analysis
X Lin, C Li, S Zhang, X Yang… - Open forum infectious …, 2024 - academic.oup.com
Background Due to scarce therapeutic options, hospital-acquired infections caused by
Klebsiella pneumoniae (KP), particularly carbapenem-resistant KP (CRKP), pose enormous …
Klebsiella pneumoniae (KP), particularly carbapenem-resistant KP (CRKP), pose enormous …
Resistome and virulome accretion in an NDM-1-producing ST147 sublineage of Klebsiella pneumoniae associated with an outbreak in Tuscany, Italy: a genotypic and …
Summary Background Carbapenemase-producing Enterobacterales (CPE), particularly
those producing metallo-β-lactamases, are among the most challenging antibiotic-resistant …
those producing metallo-β-lactamases, are among the most challenging antibiotic-resistant …
Exploring the journey: a comprehensive review of vaccine development against Klebsiella pneumoniae
B Douradinha - Microbiological Research, 2024 - Elsevier
Klebsiella pneumoniae, a prominent nosocomial pathogen, poses a critical global health
threat due to its multidrug-resistant (MDR) and hypervirulent strains. This comprehensive …
threat due to its multidrug-resistant (MDR) and hypervirulent strains. This comprehensive …
Carbapenem-resistant Klebsiella pneumoniae in high-risk haematological patients: factors favouring spread, risk factors and outcome of carbapenem-resistant …
A Micozzi, G Gentile, C Minotti, C Cartoni… - BMC infectious …, 2017 - Springer
Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) spread and
infections in patients with haematological malignancies are a serious concern especially in …
infections in patients with haematological malignancies are a serious concern especially in …
The changing epidemiology of carbapenemase-producing Klebsiella pneumoniae in Italy: toward polyclonal evolution with emergence of high-risk lineages
Background Previous studies showed that the epidemic of carbapenem-resistant Klebsiella
pneumoniae (CR-KP) observed in Italy since 2010 was sustained mostly by strains of clonal …
pneumoniae (CR-KP) observed in Italy since 2010 was sustained mostly by strains of clonal …
Diversity, Virulence, and Antimicrobial Resistance in Isolates From the Newly Emerging Klebsiella pneumoniae ST101 Lineage
The global dissemination of Klebsiella pneumoniae and Klebsiella pneumoniae
carbapenemase (KPC) has been largely attributed to a few high-risk sequence types …
carbapenemase (KPC) has been largely attributed to a few high-risk sequence types …
Molecular Epidemiology and Virulence Profiles of Colistin-Resistant Klebsiella pneumoniae Blood Isolates From the Hospital Agency “Ospedale dei Colli,” Naples …
EP Esposito, M Cervoni, M Bernardo… - Frontiers in …, 2018 - frontiersin.org
Resistance to colistin is increasingly reported in Klebsiella pneumoniae clinical isolates. The
aim of this study was to analyze the molecular epidemiology and virulence profiles of 25 …
aim of this study was to analyze the molecular epidemiology and virulence profiles of 25 …
Novel, broadly reactive anticapsular antibodies against carbapenem-resistant Klebsiella pneumoniae protect from infection
Carbapenem-resistant (CR) sequence type 258 (ST258) Klebsiella pneumoniae has
become an urgent health care threat, causing an increasing number of high-mortality …
become an urgent health care threat, causing an increasing number of high-mortality …
Computational strategies in Klebsiella pneumoniae vaccine design: navigating the landscape of in silico insights.
B Douradinha - Biotechnology Advances, 2024 - Elsevier
The emergence of multidrug-resistant Klebsiella pneumoniae poses a grave threat to global
public health, necessitating urgent strategies for vaccine development. In this context …
public health, necessitating urgent strategies for vaccine development. In this context …