Vascular dysfunction in preeclampsia

MA Opichka, MW Rappelt, DD Gutterman, JL Grobe… - Cells, 2021 - mdpi.com
Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …

Endometrial receptivity in women of advanced age: an underrated factor in infertility

ADS Pathare, M Loid, M Saare, SB Gidlöf… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Modern lifestyle has led to an increase in the age at conception. Advanced
age is one of the critical risk factors for female-related infertility. It is well known that maternal …

[HTML][HTML] BaP/BPDE suppressed endothelial cell angiogenesis to induce miscarriage by promoting MARCHF1/GPX4-mediated ferroptosis

Y Zhang, Y Yang, W Chen, C Mi, X Xu, Y Shen… - Environment …, 2023 - Elsevier
Environmental benzo (a) pyrene (BaP) and its ultimate metabolite BPDE (benzo (a) pyrene-
7, 8-dihydrodiol-9, 10-epoxide) are universal and inevitable persistent organic pollutants …

Multi-omics-based map** of decidualization resistance in patients with a history of severe preeclampsia

I Muñoz-Blat, R Pérez-Moraga, N Castillo-Marco… - Nature Medicine, 2025 - nature.com
Endometrial decidualization resistance (DR) is implicated in various gynecological and
obstetric conditions. Here, using a multi-omic strategy, we unraveled the cellular and …

Uterine natural killer cells: a rising star in human pregnancy regulation

M **e, Y Li, YZ Meng, P Xu, YG Yang, S Dong… - Frontiers in …, 2022 - frontiersin.org
Uterine natural killer (uNK) cells are an immune subset located in the uterus. uNK cells have
distinct tissue-specific characteristics compared to their counterparts in peripheral blood and …

Stromal cell senescence contributes to impaired endometrial decidualization and defective interaction with trophoblast cells

PI Deryabin, AV Borodkina - Human Reproduction, 2022 - academic.oup.com
STUDY QUESTION What are the consequences of endometrial stromal cell (EnSC)
senescence for endometrial function? SUMMARY ANSWER Senescence of EnSC …

The Known, the Unknown and the Future of the Pathophysiology of Endometriosis

MA Ochoa Bernal, AT Fazleabas - International Journal of Molecular …, 2024 - mdpi.com
Endometriosis is one of the most common causes of chronic pelvic pain and infertility,
affecting 10% of women of reproductive age. A delay of up to 9 years is estimated between …

Maternal IL-33 critically regulates tissue remodeling and type 2 immune responses in the uterus during early pregnancy in mice

N Valero-Pacheco, EK Tang, N Massri, R Loia… - Proceedings of the …, 2022 - pnas.org
The pregnant uterus is an immunologically rich organ, with dynamic changes in the
inflammatory milieu and immune cell function underlying key stages of pregnancy. Recent …

Placenta accreta spectrum diagnosis challenges and controversies in current obstetrics: a review

A Arakaza, L Zou, J Zhu - International Journal of Women's Health, 2023 - Taylor & Francis
Background Placenta accreta spectrum (PAS) is the most common obstetric complication in
current obstetrics in which the placenta is fully or partially attached to the uterine myometrial …

[HTML][HTML] The role of interleukins in recurrent implantation failure: a comprehensive review of the literature

K Pantos, S Grigoriadis, E Maziotis, K Pistola… - International journal of …, 2022 - mdpi.com
Recurrent implantation failure (RIF) is a multifactorial condition affecting 10–15% of in vitro
fertilization (IVF) couples. Data suggest that functional dysregulation of the endometrial …