Scleral structure and biomechanics

C Boote, IA Sigal, R Grytz, Y Hua, TD Nguyen… - Progress in retinal and …, 2020 - Elsevier
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …

The use of digital image correlation in the biomechanical area: a review

M Palanca, G Tozzi, L Cristofolini - International biomechanics, 2016 - Taylor & Francis
This paper offers an overview of the potentialities and limitations of digital image correlation
(DIC) as a technique for measuring displacements and strain in biomechanical applications …

IOP and glaucoma damage: The essential role of optic nerve head and retinal mechanosensors

I Pitha, L Du, TD Nguyen, H Quigley - Progress in retinal and eye research, 2024 - Elsevier
There are many unanswered questions on the relation of intraocular pressure to glaucoma
development and progression. IOP itself cannot be distilled to a single, unifying value …

[HTML][HTML] Finite element analysis predicts large optic nerve head strains during horizontal eye movements

X Wang, H Rumpel, WEH Lim… - … & visual science, 2016 - jov.arvojournals.org
Purpose: We combined finite element (FE) analysis and dynamic magnetic resonance
imaging (MRI) to estimate optic nerve head (ONH) strains during horizontal eye movements …

Optic nerve head biomechanics in aging and disease

JC Downs - Experimental eye research, 2015 - Elsevier
This nontechnical review is focused upon educating the reader on optic nerve head
biomechanics in both aging and disease along two main themes: what is known about how …

Age-and race-related differences in human scleral material properties

R Grytz, MA Fazio, V Libertiaux, L Bruno… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: We tested the hypothesis that there are age-and race-related differences in
posterior scleral material properties, using eyes from human donors of European (20–90 …

Collagen structure and mechanical properties of the human sclera: analysis for the effects of age

B Coudrillier, J Pijanka, J Jefferys… - Journal of …, 2015 - asmedigitalcollection.asme.org
The objective of this study was to measure the collagen fiber structure and estimate the
material properties of 7 human donor scleras, from age 53 to 91. The specimens were …

Material properties of the posterior human sclera

R Grytz, MA Fazio, MJA Girard, V Libertiaux… - Journal of the …, 2014 - Elsevier
To characterize the material properties of posterior and peripapillary sclera from human
donors, and to investigate the macro-and micro-scale strains as potential control …

Eye-specific IOP-induced displacements and deformations of human lamina cribrosa

IA Sigal, JL Grimm, NJ Jan, K Reid… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: To measure high-resolution eye-specific displacements and deformations induced
within the human LC microstructure by an acute increase in IOP. Methods.: Six eyes from …

Glaucoma-related changes in the mechanical properties and collagen micro-architecture of the human sclera

B Coudrillier, JK Pijanka, JL Jefferys, A Goel… - PloS one, 2015 - journals.plos.org
Objective The biomechanical behavior of the sclera determines the level of mechanical
insult from intraocular pressure to the axons and tissues of the optic nerve head, as is of …