HIV-1 infection and glucose metabolism reprogramming of T cells: another approach toward functional cure and reservoir eradication
S Kang, H Tang - Frontiers in Immunology, 2020 - frontiersin.org
With the emerging of highly active antiretroviral therapy, HIV-1 infection has transferred from
a fatal threat to a chronic disease that could be managed. Nevertheless, inextricable …
a fatal threat to a chronic disease that could be managed. Nevertheless, inextricable …
Role of Different Subpopulations of CD8+ T Cells during HIV Exposure and Infection
During HIV infection, specific responses exhibited by CD8+ T cells are crucial to establish an
early, effective, and sustained viral control, preventing severe immune alterations and organ …
early, effective, and sustained viral control, preventing severe immune alterations and organ …
Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity
K Bryniarski, W Ptak, A Jayakumar, K Püllmann… - Journal of Allergy and …, 2013 - Elsevier
Background T-cell tolerance of allergic cutaneous contact sensitivity (CS) induced in mice by
high doses of reactive hapten is mediated by suppressor cells that release antigen-specific …
high doses of reactive hapten is mediated by suppressor cells that release antigen-specific …
Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection
Spontaneous control of human immunodeficiency virus (HIV) is generally associated with an
enhanced capacity of CD8+ T cells to eliminate infected CD4+ T cells, but the molecular …
enhanced capacity of CD8+ T cells to eliminate infected CD4+ T cells, but the molecular …
Permanent control of HIV-1 pathogenesis in exceptional elite controllers: a model of spontaneous cure
Elite controllers (EC) represent a small subset of HIV-1-infected people that spontaneously
control viral replication. However, natural virological suppression and absence of immune …
control viral replication. However, natural virological suppression and absence of immune …
The effect of latency reversal agents on primary CD8+ T cells: implications for shock and kill strategies for human immunodeficiency virus eradication
VE Walker-Sperling, CW Pohlmeyer, PM Tarwater… - …, 2016 - thelancet.com
Shock and kill strategies involving the use of small molecules to induce viral transcription in
resting CD4+ T cells (shock) followed by immune mediated clearance of the reactivated cells …
resting CD4+ T cells (shock) followed by immune mediated clearance of the reactivated cells …
[HTML][HTML] Immune control of HIV
M Balasubramaniam, J Pandhare… - Journal of life sciences …, 2019 - ncbi.nlm.nih.gov
The human immunodeficiency virus (HIV) infection of the immune cells expressing the
cluster of differentiation 4 cell surface glycoprotein (CD4+ cells) causes progressive decline …
cluster of differentiation 4 cell surface glycoprotein (CD4+ cells) causes progressive decline …
Identification of NK cell subpopulations that differentiate HIV-infected subject cohorts with diverse levels of virus control
CW Pohlmeyer, VD Gonzalez, A Irrinki… - Journal of …, 2019 - Am Soc Microbiol
ABSTRACT HIV infection is controlled immunologically in a small subset of infected
individuals without antiretroviral therapy (ART), though the mechanism of control is unclear …
individuals without antiretroviral therapy (ART), though the mechanism of control is unclear …
Potential Role for HIV-Specific CD38−/HLA-DR+ CD8+ T Cells in Viral Suppression and Cytotoxicity in HIV Controllers
Background HIV controllers (HIC) are rare HIV-1-infected patients who exhibit spontaneous
viral control. HIC have high frequency of CD38−/HLA-DR+ HIV-specific CD8+ T cells. Here …
viral control. HIC have high frequency of CD38−/HLA-DR+ HIV-specific CD8+ T cells. Here …
HIV controllers: a genetically determined or inducible phenotype?
A Sáez‐Cirión, G Pancino - Immunological reviews, 2013 - Wiley Online Library
Summary Less than 0.5% of human immunodeficiency virus‐1 (HIV‐1)‐infected patients
maintain viral load below the threshold of detection by conventional assays for many years …
maintain viral load below the threshold of detection by conventional assays for many years …