The reception and integration of the plethora of signals a cell receives from its
microenvironment determines the cell's fate. CD44 functions as a receptor for hyaluronan …

Spermatogonial stem cells (SSCs) are the most primitive spermatogonia in the testis and
have an essential role to maintain highly productive spermatogenesis by self-renewal and …

Spermatogenesis is a continuous and productive process supported by the self-renewal and
differentiation of spermatogonial stem cells (SSCs), which arise from undifferentiated …

Male infertility is a multifactorial complex disease with highly heterogeneous phenotypic
representation and in at least 15% of cases, this condition is related to known genetic …

In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …

OBJECTIVE: To determine whether microRNAs are differentially expressed in men with
normal versus impaired spermatogenesis, and to find a biomarker for accurate diagnosis of …

MicroRNAs (miRNAs) are active regulators of numerous biological and physiological
processes including most of the events of mammalian reproduction. Understanding the …

MicroRNAs (miRNAs) mainly function as post-transcriptional regulators and are involved in
a wide range of physiological and pathophysiological processes such as cell proliferation …

The World Health Organization predicts that infertility will be the third major health threat
after cancer and cardiovascular disease, and will become a hot topic in medical research …

MicroRNAs applications were vastly studied throughout the years, spanning from potential
cancer biomarkers to targeted therapies for various diseases. Out of these utilizations, this …