Cytochrome P450 oxidoreductase (POR) is an enzyme that is essential for multiple
metabolic processes, chiefly among them are reactions catalyzed by cytochrome P450 …

Enzymes that catalyze the biotransformation of drugs and xenobiotics are generally referred
to as drug‐metabolizing enzymes (DMEs). DMEs can be classified into two main groups …

Ritonavir is a HIV protease inhibitor routinely prescribed to HIV patients that also potently
inactivates cytochrome P4503A4 (CYP3A4), the major human drug-metabolizing enzyme …

Mononuclear iron‐containing enzymes are highly versatile oxidants that often react
stereospecifically and/or regioselectively with substrates. Combined experimental and …

NADPH-cytochrome P450 oxidoreductase (CPR) serves as the electron donor to almost all
eukaryotic cytochromes P450. It belongs to a small family of diflavin proteins and is built of …

Methionine synthase reductase (MSR) catalyzes the conversion of the inactive form of
human methionine synthase to the active state of the enzyme. This reaction is of paramount …

Diflavin reductases are enzymes which emerged as a gene fusion of ferredoxin (flavodoxin)
reductase and flavodoxin. The enzymes of this family tightly bind two flavin cofactors, FAD …

NADPH–cytochrome P450 oxidoreductase (CYPOR) and nitric oxide synthase (NOS), two
members of the diflavin oxidoreductase family, are multi-domain enzymes containing distinct …

Many heterotrophic bacteria have the ability to make polyhedral structures containing
metabolic enzymes that are bounded by a unilamellar protein shell (metabolosomes or …

Nitric-oxide synthase (NOS), the enzyme responsible for mammalian NO generation, is no
cytochrome P450, but there are striking similarities between both enzymes. First and …