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Genetic load: genomic estimates and applications in non-model animals
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …
the mean fitness of a population, both now and in the future. This 'genetic load'has been …
Spatiotemporal omics for biology and medicine
The completion of the Human Genome Project has provided a foundational blueprint for
understanding human life. Nonetheless, understanding the intricate mechanisms through …
understanding human life. Nonetheless, understanding the intricate mechanisms through …
AVONET: morphological, ecological and geographical data for all birds
Functional traits offer a rich quantitative framework for develo** and testing theories in
evolutionary biology, ecology and ecosystem science. However, the potential of functional …
evolutionary biology, ecology and ecosystem science. However, the potential of functional …
Integrating gene annotation with orthology inference at scale
Annotating coding genes and inferring orthologs are two classical challenges in genomics
and evolutionary biology that have traditionally been approached separately, limiting …
and evolutionary biology that have traditionally been approached separately, limiting …
A species-level timeline of mammal evolution integrating phylogenomic data
High-throughput sequencing projects generate genome-scale sequence data for species-
level phylogenies,–. However, state-of-the-art Bayesian methods for inferring timetrees are …
level phylogenies,–. However, state-of-the-art Bayesian methods for inferring timetrees are …
A comparative genomics multitool for scientific discovery and conservation
Nature, 2020 - nature.com
Abstract The Zoonomia Project is investigating the genomics of shared and specialized traits
in eutherian mammals. Here we provide genome assemblies for 131 species, of which all …
in eutherian mammals. Here we provide genome assemblies for 131 species, of which all …
Complexity of avian evolution revealed by family-level genomes
Despite tremendous efforts in the past decades, relationships among main avian lineages
remain heavily debated without a clear resolution. Discrepancies have been attributed to …
remain heavily debated without a clear resolution. Discrepancies have been attributed to …
Progressive Cactus is a multiple-genome aligner for the thousand-genome era
New genome assemblies have been arriving at a rapidly increasing pace, thanks to
decreases in sequencing costs and improvements in third-generation sequencing …
decreases in sequencing costs and improvements in third-generation sequencing …
Extreme elevational migration spurred cryptic speciation in giant hummingbirds
The ecoevolutionary drivers of species niche expansion or contraction are critical for
biodiversity but challenging to infer. Niche expansion may be promoted by local adaptation …
biodiversity but challenging to infer. Niche expansion may be promoted by local adaptation …
Quality assessment of gene repertoire annotations with OMArk
In the era of biodiversity genomics, it is crucial to ensure that annotations of protein-coding
gene repertoires are accurate. State-of-the-art tools to assess genome annotations measure …
gene repertoires are accurate. State-of-the-art tools to assess genome annotations measure …