Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

The completion of the Human Genome Project has provided a foundational blueprint for
understanding human life. Nonetheless, understanding the intricate mechanisms through …

Functional traits offer a rich quantitative framework for develo** and testing theories in
evolutionary biology, ecology and ecosystem science. However, the potential of functional …

Abstract The Zoonomia Project is investigating the genomics of shared and specialized traits
in eutherian mammals. Here we provide genome assemblies for 131 species, of which all …

High-throughput sequencing projects generate genome-scale sequence data for species-
level phylogenies,–. However, state-of-the-art Bayesian methods for inferring timetrees are …

New genome assemblies have been arriving at a rapidly increasing pace, thanks to
decreases in sequencing costs and improvements in third-generation sequencing …

The rapidly emerging field of macrogenetics focuses on analysing publicly accessible
genetic datasets from thousands of species to explore large-scale patterns and predictors of …

Over 100 years of studies in Drosophila melanogaster and related species in the genus
Drosophila have facilitated key discoveries in genetics, genomics, and evolution. While high …

Annotating coding genes and inferring orthologs are two classical challenges in genomics
and evolutionary biology that have traditionally been approached separately, limiting …

Life on Earth has evolved from initial simplicity to the astounding complexity we experience
today. Bacteria and archaea have largely excelled in metabolic diversification, but …