Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs,
targeted therapeutic drugs have become mainstream cancer treatments. Since the first …

Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and
oxygen supply to the tumor cells through the decrease of the vascular network and the …

Colloidal gold has been studied for its potential application in medicine for centuries.
However, synthesis and evaluation of various gold nanoparticles have only recently been …

When Folkman first suggested a theory about the association between angiogenesis and
tumor growth in 1971, the hypothesis of targeting angiogenesis to treat cancer was formed …

Tumor cells recruit vascular endothelial cells and circulating endothelial progenitor cells to
form new vessels to support their own growth and metastasis. VEGF, PDGF-BB and FGF-2 …

A new series of benzoxazole derivatives were designed and synthesised to have the main
essential pharmacophoric features of VEGFR-2 inhibitors. Cytotoxic activities were …

Tumours require a vascular supply to grow and can achieve this via the expression of pro-
angiogenic growth factors, including members of the vascular endothelial growth factor …

Social support is defined as the perceived or actual receipt of social resources (eg, tangible,
emotional) and is one of the most reliable predictors of disease morbidity and mortality. In …

Pathological angiogenesis is a hallmark of cancer and various ischaemic and inflammatory
diseases. Concentrated efforts in this area of research are leading to the discovery of a …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …