Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

Clostridium difficile epidemiology has changed in recent years, with the emergence of highly
virulent types associated with severe infections, high rates of recurrences and mortality …

Abstract Epidemic C. difficile (027/BI/NAP1) has rapidly emerged in the past decade as the
leading cause of antibiotic-associated diarrhea worldwide. However, the key events in …

Relapsing C. difficile disease in humans is linked to a pathological imbalance within the
intestinal microbiota, termed dysbiosis, which remains poorly understood. We show that …

Clostridium difficile infection (CDI) is the leading cause of antimicrobial and health care-
associated diarrhea in humans, presenting a significant burden to global health care …

Abstract Background The epidemiology of Clostridium difficile infection (CDI) has changed
over the past decades with the emergence of highly virulent strains. The role of …

In the last three decades, Clostridium difficile infection (CDI) has increased in incidence and
severity in many countries worldwide. The increase in CDI incidence has been particularly …

The epidemiology of Clostridium difficile infection (CDI) has changed over the past decade.
There has been a dramatic worldwide increase in its incidence, and new CDI populations …

Invasive diseases caused by the globally distributed commensal yeast Candida tropicalis
are associated with mortality rates of greater than 50%. Notable increases of azole …

While Clostridium difficile infection (CDI) has come to prominence as major epidemics have
occurred in North America and Europe over the recent decade, awareness and surveillance …