Genome-resolved metagenomics: a game changer for microbiome medicine

N Kim, J Ma, W Kim, J Kim, P Belenky… - Experimental & Molecular …, 2024 - nature.com
Recent substantial evidence implicating commensal bacteria in human diseases has given
rise to a new domain in biomedical research: microbiome medicine. This emerging field …

Ecological and evolutionary forces sha** microbial diversity in the human intestine

RE Ley, DA Peterson, JI Gordon - Cell, 2006 - cell.com
The human gut is populated with as many as 100 trillion cells, whose collective genome, the
microbiome, is a reflection of evolutionary selection pressures acting at the level of the host …

Fast and flexible bacterial genomic epidemiology with PopPUNK

JA Lees, SR Harris, G Tonkin-Hill… - Genome …, 2019 - genome.cshlp.org
The routine use of genomics for disease surveillance provides the opportunity for high-
resolution bacterial epidemiology. Current whole-genome clustering and multilocus ty** …

Evolutionary dynamics of bacteria in the gut microbiome within and across hosts

NR Garud, BH Good, O Hallatschek, KS Pollard - PLoS biology, 2019 - journals.plos.org
Gut microbiota are shaped by a combination of ecological and evolutionary forces. While the
ecological dynamics have been extensively studied, much less is known about how species …

Impact of 16S rRNA gene sequence analysis for identification of bacteria on clinical microbiology and infectious diseases

JE Clarridge III - Clinical microbiology reviews, 2004 - journals.asm.org
The traditional identification of bacteria on the basis of phenotypic characteristics is
generally not as accurate as identification based on genotypic methods. Comparison of the …

Reassessing PCR primers targeting nirS, nirK and nosZ genes for community surveys of denitrifying bacteria with DGGE

IN Throbäck, K Enwall, Å Jarvis… - FEMS microbiology …, 2004 - academic.oup.com
We re-evaluated PCR primers targeting nirS, nirK and nosZ genes for denaturing gradient
gel electrophoresis as a tool to survey denitrifying community composition in environmental …

The Population Structure of Acinetobacter baumannii: Expanding Multiresistant Clones from an Ancestral Susceptible Genetic Pool

L Diancourt, V Passet, A Nemec, L Dijkshoorn… - PloS one, 2010 - journals.plos.org
Outbreaks of hospital infections caused by multidrug resistant Acinetobacter baumannii
strains are of increasing concern worldwide. Although it has been reported that particular …

[HTML][HTML] Then and now: use of 16S rDNA gene sequencing for bacterial identification and discovery of novel bacteria in clinical microbiology laboratories

PCY Woo, SKP Lau, JLL Teng, H Tse… - Clinical Microbiology and …, 2008 - Elsevier
In the last decade, as a result of the widespread use of PCR and DNA sequencing, 16S
rDNA sequencing has played a pivotal role in the accurate identification of bacterial isolates …

16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates

M Drancourt, C Bollet, A Carlioz… - Journal of clinical …, 2000 - journals.asm.org
Some bacteria are difficult to identify with phenotypic identification schemes commonly used
outside reference laboratories. 16S ribosomal DNA (rDNA)-based identification of bacteria …

Report of the ad hoc committee for the re-evaluation of the species definition in bacteriology.

E Stackebrandt, W Frederiksen… - … of systematic and …, 2002 - microbiologyresearch.org
An ad hoc committee for the re-evaluation of the species definition in bacteriology met in
Gent, Belgium, in February 2002. The committee made various recommendations regarding …