PM2. 5 exposure and asthma development: the key role of oxidative stress

K Liu, S Hua, L Song - Oxidative medicine and cellular …, 2022 - Wiley Online Library
Oxidative stress is defined as the imbalance between reactive oxygen species (ROS)
production and the endogenous antioxidant defense system, leading to cellular damage …

Nuclear factor-κB—a pivotal transcription factor in chronic inflammatory diseases

PJ Barnes, M Karin - New England journal of medicine, 1997 - Mass Medical Soc
In chronic inflammatory diseases, such as asthma, rheumatoid arthritis, inflammatory bowel
disease, and psoriasis, several cytokines recruit activated immune and inflammatory cells to …

[PDF][PDF] Nitric oxide and superoxide in inflammation

T Guzik, R Korbut, T Adamek-Guzik - J physiol pharmacol, 2003 - jpp.krakow.pl
Nitric oxide (NO) and reactive oxygen species exert multiple modulating effects on
inflammation and play a key role in the regulation of immune responses. They affect virtually …

Asthma: from bronchoconstriction to airways inflammation and remodeling

J Bousquet, PK Jeffery, WW Busse… - American journal of …, 2000 - atsjournals.org
Asthma | From Bronchoconstriction to Airways Inflammation and Remodeling | American
Journal of Respiratory and Critical Care Medicine ATS Journals Logo Official Publications …

Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension

A Giaid, D Saleh - New England Journal of Medicine, 1995 - Mass Medical Soc
Background Pulmonary hypertension is characterized by abnormal thickening of the
pulmonary arteries and increased pulmonary vascular resistance. Nitric oxide is a potent …

Nitric oxide in health and disease of the respiratory system

FLM Ricciardolo, PJ Sterk, B Gaston… - Physiological …, 2004 - journals.physiology.org
During the past decade a plethora of studies have unravelled the multiple roles of nitric
oxide (NO) in airway physiology and pathophysiology. In the respiratory tract, NO is …

Inducible nitric oxide synthase and inflammatory diseases

R Zamora, Y Vodovotz, TR Billiar - Molecular medicine, 2000 - Springer
Nitric oxide (NO) is a colorless gas at room temperature and one of the simplest molecules
known, yet it has been implicated in a wide variety of regulatory mechanisms ranging from …

A review of breath analysis for diagnosis of human health

KH Kim, SA Jahan, E Kabir - TrAC Trends in Analytical Chemistry, 2012 - Elsevier
In this review, we describe technical developments in breath analysis and its applications in
clinical diagnosis, monitoring disease state, and assessing environmental exposure. Breath …

Exhaled markers of pulmonary disease

SA Kharitonov, PJ Barnes - … journal of respiratory and critical care …, 2001 - atsjournals.org
There has recently been an explosion of interest in the analysis of breath constituents as a
way of monitoring inflammation and oxidative stress in the lungs. Here we review the use of …

Inducible nitric oxide synthase in human diseases

KD Kröncke, K Fehsel… - Clinical & experimental …, 1998 - academic.oup.com
Since its discovery as a biologically active molecule in the late 1980s, nitric oxide (NO) has
been found to play an important role as signal molecule in many parts of the organism as …