Adipose tissue not only has an important role in the storage of excess nutrients but also
senses nutrient status and regulates energy mobilization. An overall positive energy balance …

The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …

Hypoxia develops in white adipose tissue in obese mice, resulting in changes in adipocyte
function that may underpin the dysregulation that leads to obesity-associated disorders …

The number of studies in the field of adipose tissue biology has increased exponentially
over the last decade. This shift in research focus is primarily driven by the tremendous …

Abstract Background: Angiopoietin-like 4 (ANGPTL4) belongs to the angiopoietin-like
protein family and mediates the inhibition of lipoprotein lipase activity. Emerging evidence …

Obesity has emerged as one of the major health threats worldwide. Moreover, an excessive
body fat accumulation, which defines this disease, could lead to several associated clinical …

The prevalence of obesity and diabetes is increasing worldwide. Obesity and diabetes are
associated with oxidative stress, inflammation, endothelial dysfunction, insulin resistance …

Oxygen pressure plays an integral role in regulating various aspects of cellular biology. Cell
metabolism, proliferation, morphology, senescence, metastasis, and angiogenesis are some …

Lung inflammation and alveolar epithelial cell death are critical events in the development
and progression of acute lung injury (ALI). Although angiopoietin‐like protein 4 (ANGPTL4) …

Adipose tissue hypoxia has been demonstrated in animal models of obesity, but findings in
humans are controversial and require further investigation. Although adipose tissue PO 2 …